Results 1 to 10 of about 53 (53)

Overexpression of BNIP3 in rat intervertebral disk cells triggers autophagy and apoptosis [PDF]

open access: yesArchives of Biological Sciences, 2022
Excessive apoptosis of intervertebral disk cells and intervertebral disk degeneration (IDD) is the prime cause of low back pain. B-cell lymphoma 2 (Bcl-2) and adenovirus E1B 19 kDa interacting protein 3 (BNIP3), a member of the Bcl-2 family, are involved
Tingsheng Wu   +5 more
doaj   +1 more source

CALCOCO1 in the progression of malignant tumors [PDF]

open access: yesJichu yixue yu linchuang, 2023
Calcium binding and coiled-coil domain 1 (CALCOCO1) is an autophagy regulatory protein being discovered in recent years, which plays an important role in selective autophagy process.
JIA Nan, WANG Zhilian
doaj   +1 more source

Autophagy Inhibits Intercellular Transport of Citrus Leaf Blotch Virus by Targeting Viral Movement Protein

open access: yesViruses, 2021
Autophagy is an evolutionarily conserved cellular-degradation mechanism implicated in antiviral defense in plants. Studies have shown that autophagy suppresses virus accumulation in cells; however, it has not been reported to specifically inhibit viral ...
Erbo Niu   +6 more
doaj   +1 more source

AeiA, an Atg8-interacting protein in Aspergillus oryzae, promotes peroxisome degradation by pexophagy

open access: yesAutophagy Reports, 2023
There are two types of autophagy, non-selective (bulk) autophagy, in which substrates are randomly incorporated into autophagosomes, and selective autophagy, in which substrates are specifically targeted.
Takashi Kikuma, Joichiro Nishio
doaj   +1 more source

DNAJB12 and Hsp70 Mediate Triage of Misfolded Membrane Proteins for Proteasomal versus Lysosomal Degradation

open access: yesAutophagy Reports, 2022
The endoplasmic reticulum (ER) fills the cell with a continuous network of sealed membrane tubules and sheets. The ER is subdivided into microdomains mediating one-third of total protein biosynthesis, oxidative protein folding, secretion, protein quality
Andrew Kennedy, Douglas M. Cyr
doaj   +1 more source

Aquaporin-8 transports hydrogen peroxide to regulate granulosa cell autophagy

open access: yesFrontiers in Cell and Developmental Biology, 2022
Aquaporin-8 (AQP8), a member of the aquaporin family, is strongly expressed in follicular granulosa cells, which could affect the hormone secretion level in females.
Binbin Huang   +9 more
doaj   +1 more source

Autophagy safeguards conidial environmental persistence in filamentous fungi

open access: yesAutophagy Reports, 2023
Conidiation mechanism confers filamentous fungus efficient dispersal and survival in natural habitats. However, the mechanisms that regulate conidial lifespan and persistence remain enigmatic.
Jin-Li Ding   +2 more
doaj   +1 more source

STX17 improves Aβ31-35 induced death of hippocampal neurons in mice

open access: yes陆军军医大学学报, 2022
Objective To explore the role of STX17 protein in Aβ-induced death of mouse hippocampal neuronal cells. Methods Based on Weighted correlation network analysis (WGCNA), the modules significantly related to Alzheimer's disease (AD) were selected, and key ...
WANG Ning   +4 more
doaj   +1 more source

Differential effects of concomitant use of vitamins C and E on trophoblast apoptosis and autophagy between normoxia and hypoxia-reoxygenation. [PDF]

open access: yesPLoS ONE, 2010
BackgroundConcomitant supplementation of vitamins C and E during pregnancy has been reportedly associated with low birth weight, the premature rupture of membranes and fetal loss or perinatal death in women at risk for preeclampsia; however, the cause is
Tai-Ho Hung   +4 more
doaj   +1 more source

Multi-Omics Analysis of the Expression and Prognosis for FKBP Gene Family in Renal Cancer

open access: yesFrontiers in Oncology, 2021
BackgroundThe FK506-binding protein (FKBP) is a family of intracellular receptors that can bind specifically to the immunosuppressant FK506 and rapamycin.
Zeqiang Sun   +4 more
doaj   +1 more source

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