Results 1 to 10 of about 429 (86)

Multiple Functions of ATG8 Family Proteins in Plant Autophagy

open access: yesFrontiers in Cell and Developmental Biology, 2020
Autophagy is a major degradation process of cytoplasmic components in eukaryotes, and executes both bulk and selective degradation of targeted cargos.
Liang Chen
exaly   +3 more sources

Atg8-Family Proteins—Structural Features and Molecular Interactions in Autophagy and Beyond

open access: yesCells, 2020
Autophagy is a common name for a number of catabolic processes, which keep the cellular homeostasis by removing damaged and dysfunctional intracellular components.
Vladimir Kirkin   +2 more
exaly   +3 more sources

Atg8ylation as a general membrane stress and remodeling response

open access: yesCell Stress, 2021
The yeast Atg8 protein and its paralogs in mammals, mammalian Atg8s (mAtg8s), have been primarily appreciated for their participation in autophagy. However, lipidated mAtg8s, including the most frequently used autophagosomal membrane marker LC3B, are ...
Suresh Kumar, Jingyue Jia1, Vojo Deretic
doaj   +1 more source

Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase [PDF]

open access: yesOpen Biology, 2015
The network of protein–protein interactions of the Dictyostelium discoideum autophagy pathway was investigated by yeast two-hybrid screening of the conserved autophagic proteins Atg1 and Atg8.
Ana Mesquita   +5 more
doaj   +1 more source

Structure-Function Relationship for a Divergent Atg8 Protein Required for a Nonautophagic Function in Apicomplexan Parasites

open access: yesmBio, 2023
Atg8 family proteins are highly conserved eukaryotic proteins with diverse autophagy and nonautophagic functions in eukaryotes. While the structural features required for conserved autophagy functions of Atg8 are well established, little is known about ...
Marta Walczak   +5 more
doaj   +1 more source

Atg4 plays an important role in efficient expansion of autophagic isolation membranes by cleaving lipidated Atg8 in Saccharomyces cerevisiae. [PDF]

open access: yesPLoS ONE, 2017
Autophagy, an intracellular degradation system, is highly conserved among eukaryotes from yeast to mammalian cells. In the yeast Saccharomyces cerevisiae, most Atg (autophagy-related) proteins, which are essential for autophagosome formation, are ...
Eri Hirata   +2 more
doaj   +1 more source

Proteomic analysis of Atg8-dependent recruitment of phagosomal proteins in the enteric protozoan parasite Entamoeba histolytica

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Autophagy is one of the bulk degradation systems and is conserved throughout eukaryotes. In the enteric protozoan parasite Entamoeba histolytica, the causative agent of human amebiasis, Atg8 is not exclusively involved in autophagy per se but also in ...
Kumiko Nakada-Tsukui   +5 more
doaj   +1 more source

AeiA, an Atg8-interacting protein in Aspergillus oryzae, promotes peroxisome degradation by pexophagy

open access: yesAutophagy Reports, 2023
There are two types of autophagy, non-selective (bulk) autophagy, in which substrates are randomly incorporated into autophagosomes, and selective autophagy, in which substrates are specifically targeted.
Takashi Kikuma, Joichiro Nishio
doaj   +1 more source

Coordinated recruitment of conserved defense-signaling pathways in PVYO-Infected Nicotiana benthamiana

open access: yesPlant Signaling & Behavior, 2023
Potato virus Y (PVY) is an aphid-transmitted potyvirus that affects economically important solanaceous species. In this study, the phenomena and mechanisms following infection with PVY were investigated in tobacco (Nicotiana benthamiana).
Won-Jin Kim   +4 more
doaj   +1 more source

Atg8 family proteins, LIR/AIM motifs and other interaction modes

open access: yesAutophagy Reports, 2023
The Atg8 family of ubiquitin-like proteins play pivotal roles in autophagy and other processes involving vesicle fusion and transport where the lysosome/vacuole is the end station. Nuclear roles of Atg8 proteins are also emerging.
Vladimir V. Rogov   +16 more
doaj   +1 more source

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