Results 1 to 10 of about 166,195 (340)

Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses

Nature Communications, 2017
Selective autophagy describes the selective degradation of cellular components upon stress or nutrient deficiency, but whether it modulates innate immunity is unclear.
Radu Tusco, Anne-Claire Jacomin, Ashish Jain, Bridget S. Penman, Kenneth Bowitz Larsen, Terje Johansen, Ioannis P. Nezis   +6 more
doaj   +1 more source

Compromised autophagy in the aging epididymis: Evidence and relevance to male fertility

Experimental Gerontology
Impaired autophagy and increased cellular senescence in the aging epididymis may lead to cellular stress, inflammation, and epithelial dysfunction. This reduction in autophagy can be identified using light and electron microscopy, as well as molecular ...
Nabil Eid
doaj   +1 more source

Selective Inhibitors of Autophagy Reveal New Link between the Cell Cycle and Autophagy and Lead to Discovery of Novel Synergistic Drug Combinations

, 2022
Kisa Sung, Agata Kurowski, Carisse Lansiquot, Kanny K. Wan, Samarjit Patnaik, Martin J. Walsh, Michael B. Lazarus   +6 more
openalex   +2 more sources

NBR1a mediates root-knot nematode resistance by modulating antioxidant system, jasmonic acid and selective autophagy in Solanum lycopersicum

Plant Stress
Root-knot nematodes (RKNs; Meloidogyne incognita) are recognized as the most destructive plant pathogenic nematodes, posing a significant threat to global food security.
Ting Yang, Weiduo Jin, Jinping Zou, Xinlin Chen, Qiufeng Zhao, Jingquan Yu, Jie Zhou   +6 more
doaj   +1 more source

The Protective Effects of Κ-Opioid Receptor Stimulation in Hypoxic Pulmonary Hypertension Involve Inhibition of Autophagy Through the AMPK-MTOR Pathway

Cellular Physiology and Biochemistry, 2017
Background/Aims: In a previous study, we showed that κ-opioid receptor stimulation with the selective agonist U50,488H ameliorated hypoxic pulmonary hypertension (HPH).
Yaguang Zhou, Yuanbo Wang, Xu Wang, Xin Tian, Shumiao Zhang, Fan Yang, Haitao Guo, Rong Fan, Na Feng, Min Jia, Xiaoming Gu, Yuemin Wang, Juan Li, Jianming Pei   +13 more
doaj   +1 more source

The role of Tecpr1 in selective autophagy as a cargo receptor [PDF]

, 2011
Michinaga Ogawa, Chihiro Sasakawa
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Glycophagy – the Physiological Perspective on A Newly Characterized Glycogen-Selective Autophagy

, 2022
Lea M.D. Delbridge, Parisa Koutsifeli, Sarah P.T. Fong, Marco Annandale, Kate L. Weeks, James R. Bell, Kimberley M. Mellor   +6 more
openalex   +2 more sources

Autophagy in Cancer Cell Death

Biology, 2019
Autophagy has important functions in maintaining energy metabolism under conditions of starvation and to alleviate stress by removal of damaged and potentially harmful cellular components. Therefore, autophagy represents a pro-survival stress response in
Benedikt Linder, Donat Kögel
doaj   +1 more source

Ubr1-induced selective endo-phagy/autophagy protects against the endosomal and Ca ²⁺ -induced proteostasis disease stress [PDF]

, 2021
Ben B. Wang, Haijin Xu, Sandra Isenmann, Cheng Huang, Xabier Elorza‐Vidal, Grigori Y. Rychkov, Raúl Estévez, Ralf B. Schittenhelm, Gergely L. Lukács, Pirjo M. Apaja   +9 more
openalex   +1 more source

Chiral polymer modified nanoparticles selectively induce autophagy of cancer cells for tumor ablation

Journal of Nanobiotechnology, 2018
Background Autophagy regulation through exogenous materials has aroused intensive attention to develop treatment protocols according to diverse human diseases.
Long Yuan, Fan Zhang, Xiaowei Qi, Yongjun Yang, Chang Yan, Jun Jiang, Jun Deng   +6 more
doaj   +1 more source