Results 21 to 30 of about 1,158,330 (246)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) [PDF]
, 2022 Funding: This work was supported by the National Institute of General Medical Sciences [GM131919].In 2008, we published the first set of guidelines for standardizing research in autophagy.
Autophagy Group +2 more
core +2 more sources
Role of Macroautophagy in Mammalian Male Reproductive Physiology
Cells, 2023 Physiologically, autophagy is an evolutionarily conserved and self-degradative process in cells. Autophagy carries out normal physiological roles throughout mammalian life.
Doaa Kirat +4 more
doaj +1 more source
Cells, 2021 Nuclear autophagy is an important selective autophagy process. The selective autophagy of sexual development micronuclei (MICs) and the programmed nuclear degradation of parental macronucleus (paMAC) occur during sexual reproduction in Tetrahymena ...
Tao Bo +4 more
doaj +1 more source
Selective autophagy controls innate immune response through a TAK1/TAB2/SH3PX1 axis
Cell Reports, 2022 Summary: Selective autophagy is a catabolic route that turns over specific cellular material for degradation by lysosomes, and whose role in the regulation of innate immunity is largely unexplored.
Panagiotis Tsapras +7 more
doaj +1 more source
NBR1: The archetypal selective autophagy receptor [PDF]
, 2022 NBR1 was discovered as an autophagy receptor not long after the first described vertebrate autophagy receptor p62/SQSTM1. Since then, p62 has currently been mentioned in >10,000 papers on PubMed, while NBR1 is mentioned in
Lamark, Trond +3 more
core +1 more source
Identification and functional analysis of Joka2, a tobacco member of the family of selective autophagy cargo receptors [PDF]
, 2011 Two main mechanisms of protein turnover exist in eukaryotic cells: the ubiquitin-proteasome system and the autophagylysosomal pathway. Autophagy is an emerging important constituent of many physiological and pathological processes, such as response to ...
Sirko, Agnieszka +17 more
core +1 more source
mBio, 2021 Mycobacterium tuberculosis (Mtb) causes one of the deadliest infectious diseases worldwide. Upon infection, Mtb is phagocytosed by macrophages and uses its virulence-associated ESX-1 secretion system to modulate the host cell.
Samantha L. Bell +4 more
doaj +1 more source
CALCOCO1 in the progression of malignant tumors [PDF]
Jichu yixue yu linchuang, 2023 Calcium binding and coiled-coil domain 1 (CALCOCO1) is an autophagy regulatory protein being discovered in recent years, which plays an important role in selective autophagy process.
JIA Nan, WANG Zhilian
doaj +1 more source
Autophagy in Drosophila : from historical studies to current knowledge [PDF]
, 2014 The discovery of evolutionarily conserved Atg genes required for autophagy in yeast truly revolutionized this research field, and made it possible to carry out functional studies in model organisms.
Nezis, I. P. +13 more
core +1 more source
Selective Autophagy in Drosophila
International Journal of Cell Biology, 2012 Autophagy is an evolutionarily conserved process of cellular self-eating and is a major pathway for degradation of cytoplasmic material by the lysosomal machinery.
Ioannis P. Nezis
doaj +1 more source