Results 11 to 20 of about 98,515 (154)
Selective Autophagy in Drosophila [PDF]
International Journal of Cell Biology, 2012 Autophagy is an evolutionarily conserved process of cellular self-eating and is a major pathway for degradation of cytoplasmic material by the lysosomal machinery.
Ioannis P. Nezis
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The Selectivity and Specificity of Autophagy in Drosophila [PDF]
Cells, 2012 Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Ioannis P. Nezis
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Receptor Proteins in Selective Autophagy [PDF]
International Journal of Cell Biology, 2012 Autophagy has long been thought to be an essential but unselective bulk degradation pathway. However, increasing evidence suggests selective autophagosomal turnover of a broad range of substrates.
Christian Behrends, Simone Fulda
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Autophagy, selective autophagy, and necroptosis in COPD
International Journal of COPD, 2018 Kenji Mizumura, Shuichiro Maruoka, Tetsuo Shimizu, Yasuhiro Gon Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan Abstract: COPD is characterized by persistent respiratory symptoms and ...
Mizumura K, Maruoka S, Shimizu T, Gon Y
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Cancer Science, 2021 AbstractWhile starvation‐induced autophagy is thought to randomly degrade cellular components, under certain circumstances autophagy selectively recognizes, sequesters, and degrades specific targets via autophagosomes. This process is called selective autophagy, and it contributes to cellular homeostasis by degrading specific soluble proteins ...
Mohammad Omar Faruk +2 more
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Selective Types of Autophagy [PDF]
International Journal of Cell Biology, 2012 The focus of this special issue of the International Journal of Cell Biology is to underscore the recent developments in the field of macroautophagy and how this degradative pathway intersects with cellular metabolism, complex physiological functions, and human diseases. During the last decade, autophagy has become an expanding field in biomedical life
Fulvio Reggiori +3 more
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Ubiquitination and selective autophagy [PDF]
Cell Death & Differentiation, 2012 Ubiquitination has long been recognised as a key determinator of protein fate by tagging proteins for proteasomal degradation. Most recently, the ability of conjugated ubiquitin chains to confer selectivity to autophagy was demonstrated. Although autophagy was first believed to be a bulk, non-selective 'self-eating' degradative process, the molecular ...
Shaid S, Brandts CH, Serve H, Dikic I.
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Selective autophagy: Lysophagy [PDF]
Methods, 2015 Autophagy is a bulk degradation system that is induced under stress conditions such as nutrient deprivation. Selective autophagy, including xenophagy and mitophagy, is believed to play important roles in the development of several diseases. Consequently, selective autophagy represents a potential therapeutic target. Recent work showed that the lysosome,
Junya, Hasegawa +3 more
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Selective autophagy: Xenophagy [PDF]
Methods, 2015 Xenophagy is an autophagic phenomenon that specifically involves pathogens and other non-host entities. Although the understanding of the relationship between autophagosomes and invading organisms has grown significantly in the past decade, the exact steps to confirm xenophagy has been not been thoroughly defined. Here we describe a methodical approach
Kyle A, Bauckman +2 more
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Selective autophagy and viruses [PDF]
Autophagy, 2011 In recent years, the process of selective autophagy has received much attention with respect to the clearance of protein aggregates, damaged mitochondria and bacteria. However, until recently, there have been virtually no studies on the selective autophagy of viruses, although they are perhaps one of the most ubiquitous unwanted constituents in human ...
Rhea, Sumpter, Beth, Levine
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