Results 11 to 20 of about 166,195 (340)

The Selectivity and Specificity of Autophagy in Drosophila [PDF]

open access: goldCells, 2012
Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Ioannis P. Nezis
doaj   +6 more sources

Receptor Proteins in Selective Autophagy [PDF]

open access: yesInternational Journal of Cell Biology, 2012
Autophagy has long been thought to be an essential but unselective bulk degradation pathway. However, increasing evidence suggests selective autophagosomal turnover of a broad range of substrates.
Christian Behrends, Simone Fulda
doaj   +6 more sources

Selective Autophagy by Close Encounters of the Ubiquitin Kind [PDF]

open access: goldCells, 2020
Autophagy, a bulk degradation process within eukaryotic cells, is responsible for cellular turnover and nutrient liberation during starvation. Increasing evidence indicate that this process can be extremely discerning.
Anna Vainshtein, Paolo Grumati
doaj   +2 more sources

Herpesvirus Regulation of Selective Autophagy [PDF]

open access: yesViruses, 2021
Selective autophagy has emerged as a key mechanism of quality and quantity control responsible for the autophagic degradation of specific subcellular organelles and materials.
Mai Tram Vo, Young Bong Choi
doaj   +3 more sources

The multifaceted functions of selective autophagy in cancer: molecular basis, consequences, and clinical prospects [PDF]

open access: yesMolecular Cancer
Selective autophagy is a critical cellular process in eukaryotic cells, characterized by the targeted degradation of specific organelles and proteins.
Mingyang Jiang   +19 more
doaj   +2 more sources

Selective Autophagy in Drosophila [PDF]

open access: yesInternational Journal of Cell Biology, 2012
Autophagy is an evolutionarily conserved process of cellular self-eating and is a major pathway for degradation of cytoplasmic material by the lysosomal machinery.
Ioannis P. Nezis
doaj   +3 more sources

Targeting selective autophagy and beyond: From underlying mechanisms to potential therapies [PDF]

open access: yesJournal of Advanced Research
Background: Autophagy is an evolutionarily conserved turnover process for intracellular substances in eukaryotes, relying on lysosomal (in animals) or vacuolar (in yeast and plants) mechanisms.
Wei Ma   +5 more
doaj   +2 more sources

Mechanism of autophagy initiation by transmembrane selective autophagy receptors [PDF]

open access: yesThe EMBO Journal
Selective autophagy ensures the targeted degradation of damaged or surplus cellular components, including organelles, thereby safeguarding cellular homeostasis.
Elias Adriaenssens, Sascha Martens
doaj   +2 more sources

Upregulated pexophagy limits the capacity of selective autophagy [PDF]

open access: yesNature Communications
Selective autophagy is an essential process to maintain cellular homeostasis through the constant recycling of damaged or superfluous components. Over a dozen selective autophagy pathways mediate the degradation of diverse cellular substrates, but ...
Kyla Germain   +5 more
doaj   +2 more sources

Autophagy, selective autophagy, and necroptosis in COPD

open access: yesInternational Journal of COPD, 2018
Kenji Mizumura, Shuichiro Maruoka, Tetsuo Shimizu, Yasuhiro Gon Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan Abstract: COPD is characterized by persistent respiratory symptoms and ...
Mizumura K, Maruoka S, Shimizu T, Gon Y
doaj   +4 more sources

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