Results 11 to 20 of about 1,158,330 (246)
The Selectivity and Specificity of Autophagy in Drosophila [PDF]
Cells, 2012 Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Ioannis P. Nezis
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Receptor Proteins in Selective Autophagy [PDF]
International Journal of Cell Biology, 2012 Autophagy has long been thought to be an essential but unselective bulk degradation pathway. However, increasing evidence suggests selective autophagosomal turnover of a broad range of substrates.
Christian Behrends, Simone Fulda
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Implications of Selective Autophagy Dysfunction for ALS Pathology
Cells, 2020 Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disorder that progressively affects motor neurons in the brain and spinal cord. Due to the biological complexity of the disease, its etiology remains unknown.
Emiliano Vicencio +5 more
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Selective Autophagy by Close Encounters of the Ubiquitin Kind
Cells, 2020 Autophagy, a bulk degradation process within eukaryotic cells, is responsible for cellular turnover and nutrient liberation during starvation. Increasing evidence indicate that this process can be extremely discerning.
Anna Vainshtein, Paolo Grumati
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Ubiquitin, Autophagy and Neurodegenerative Diseases
Cells, 2020 Ubiquitin signals play various roles in proteolytic and non-proteolytic functions. Ubiquitin signals are recognized as targets of the ubiquitin–proteasome system and the autophagy–lysosome pathway.
Yoshihisa Watanabe +2 more
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Broad and Complex Roles of NBR1-Mediated Selective Autophagy in Plant Stress Responses
Cells, 2020 Selective autophagy is a highly regulated degradation pathway for the removal of specific damaged or unwanted cellular components and organelles such as protein aggregates.
Yan Zhang, Zhixiang Chen
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Autophagy, selective autophagy, and necroptosis in COPD
International Journal of COPD, 2018 Kenji Mizumura, Shuichiro Maruoka, Tetsuo Shimizu, Yasuhiro Gon Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan Abstract: COPD is characterized by persistent respiratory symptoms and ...
Mizumura K, Maruoka S, Shimizu T, Gon Y
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Glycogen Granules Are Degraded by Non-Selective Autophagy in Nitrogen-Starved Komagataella phaffii
CellsAutophagy was initially recognized as a bulk degradation process that randomly sequesters and degrades cytoplasmic material in lysosomes (vacuoles in yeast). In recent years, various types of selective autophagy have been discovered.
Nimna V. Wijewantha +2 more
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Tracking autophagy during proliferation and differentiation of Trypanosoma brucei [PDF]
, 2014 Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Mottram, Jeremy +3 more
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Early endosomes and endosomal coatomer are required for autophagy [PDF]
, 2009 Autophagy, an intracellular degradative pathway, maintains cell homeostasis under normal and stress conditions. Nascent double-membrane autophagosomes sequester and enclose cytosolic components and organelles, and subsequently fuse with the endosomal ...
Tooze, Sharon A. +2 more
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