Results 11 to 20 of about 160,386 (240)

Autoradiography reveals regional metabolic differences in the endometrium of pregnant and nonpregnant mice

Brazilian Journal of Medical and Biological Research, 1998
The rodent endometrium undergoes remarkable modifications during pregnancy, resulting from a redifferentiation of its fibroblasts. During this modification (decidualization), the fibroblasts transform into large, polyhedral cells that establish ...
S.F. Oliveira, P. Abrahamsohn, T.M.T. Zorn   +2 more
doaj   +1 more source

Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography [PDF]

, 2011
Accurate identification of ischemic penumbra will improve stroke patient selection for reperfusion therapies and clinical trials. Current magnetic resonance imaging (MRI) techniques have limitations and lack validation.
Barrie Condon, Celestine Santosh, Christopher McCabe, Craig A Robertson, I Mhairi Macrae, Keith W Muir, Kucinski T, Lindsay Gallagher, Maria del Rosario Lopez-Gonzalez, William M Holmes   +9 more
core   +1 more source

Mechanistic Insights into the Stimulant Properties of Novel Psychoactive Substances (NPS) and Their Discrimination by the Dopamine Transporter—In Silico and In Vitro Exploration of Dissociative Diarylethylamines

Brain Sciences, 2018
Novel psychoactive substances (NPS) may have unsuspected addiction potential through possessing stimulant properties. Stimulants normally act at the dopamine transporter (DAT) and thus increase dopamine (DA) availability in the brain, including nucleus ...
Michelle A. Sahai, Colin Davidson, Neelakshi Dutta, Jolanta Opacka-Juffry   +3 more
doaj   +1 more source

Hyperglycaemia does not increase perfusion deficits after focal cerebral ischaemia in male Wistar rats [PDF]

, 2018
Background: Hyperglycaemia is associated with a worse outcome in acute ischaemic stroke patients; yet the pathophysiological mechanisms of hyperglycaemia-induced damage are poorly understood.
Dewar, Deborah, Holmes, William M., MacDonald, Kathleen, Macrae, I. Mhairi, Muir, Keith W., Thow, Lisa A.   +5 more
core   +1 more source

Receptor localization of steroid hormones and drugs: discoveries through the use of thaw-mount and dry-mount autoradiography

Brazilian Journal of Medical and Biological Research, 1998
The history of receptor autoradiography, its development and applications, testify to the utility of this histochemical technique for localizing radiolabeled hormones and drugs at cellular and subcellular sites of action in intact tissues.
W.E. Stumpf
doaj   +1 more source

Automated quantitative analysis of single and double label autoradiographs [PDF]

, 1979
A method for the analysis of silver grain content in both single and double label autoradiographs is presented. The total grain area is calculated by counting the number of pixels at which the recorded light intensity in transmission dark field ...
Aus, H. M., Harms, H., Haucke, M., Kellerer, Albrecht M., Korr, H., Maurer-Schultze, B., Meulen, V. ter, Ruter, A.   +7 more
core   +1 more source

Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n–3 polyunsaturated fatty acids

Journal of Lipid Research, 2000
We studied the effects of a diet chronically deficient in α-linolenic acid, the precursor of long-chain n–3 polyunsaturated fatty acids, on dopaminergic neurotransmission in the shell region of the nucleus accumbens of rats.
Luc Zimmer, Sylvie Delion-Vancassel, Georges Durand, Denis Guilloteau, Sylvie Bodard, Jean-Claude Besnard, Sylvie Chalon   +6 more
doaj   +1 more source

Uranium Traps in Phreatic Sandstone-type Prospect, Taunsa Area, Dera Ghazi Khan, Eastern Sulaiman Range, Pakistan: Evidences from Autoradiography and Optical Microscopy

International Journal of Economic and Environment Geology, 2020
Taunsa uranium occurrence like other uranium resources in Pakistan is hosted by the Late Miocene-Pliocene age Litra Formation of the Siwalik Group molasse sediments.
Rahman Ullah, Nie Fengjuin, Zhang Xin, Zhang Chengyong, Asim Ali, Zhang Pengfei
doaj   +1 more source

[¹²⁵I]INFT: Synthesis and Evaluation of a New Imaging Agent for Tau Protein in Post-Mortem Human Alzheimer’s Disease Brain

Molecules, 2023
Aggregation of Tau protein into paired helical filaments causing neurofibrillary tangles (NFT) is a neuropathological feature in Alzheimer’s disease (AD).
Roz R. Limpengco, Christopher Liang, Yasmin K. Sandhu, Jogeshwar Mukherjee   +3 more
doaj   +1 more source

Exclusive neuronal expression of SUCLA2 in the human brain [PDF]

, 2013
SUCLA2 encodes the ATP-forming subunit (A-SUCL-) of succinyl-CoA ligase, an enzyme of the citric acid cycle. Mutations in SUCLA2 lead to a mitochondrial disorder manifesting as encephalomyopathy with dystonia, deafness and lesions in the basal ganglia ...
A Kowluru, A Minelli, A Navarro-Sastre, A Rotig, A Vozza, AA Gerencser, AC Yu, Aniko Gál, Arpád Dobolyi, Attila G. Bagó, B Przybyla-Zawislak, C Chinopoulos, C Chinopoulos, C Chinopoulos, C Chinopoulos, C Chinopoulos, C Miller, Christos Chinopoulos, DO Lambeth, E Brekke, E Ostergaard, E Ostergaard, E Ostergaard, E Ostergaard, E Pfaff, EE McKee, EE McKee, EF Kadrmas, Elsebet Ostergaard, F Conti, F Conti, G Kiss, JC Wallace, JD Johnson, JH Ottaway, L Milon, M Lopes-Cardozo, M Palkovits, M Thomson, Miklós Palkovits, ML Pall, Mária J. Molnár, N Westergaard, O Elpeleg, R Carrozzo, R Dringen, RF Labbe, RL Strausberg, RP Shank, S Tanner, Tamás Dóczi, TM Jenkins, U Sonnewald, Vera Adam-Vizi, X Li, Z Zhang   +55 more
core   +2 more sources