Results 21 to 30 of about 193,799 (312)

Autoradiography reveals regional metabolic differences in the endometrium of pregnant and nonpregnant mice

Brazilian Journal of Medical and Biological Research, 1998
The rodent endometrium undergoes remarkable modifications during pregnancy, resulting from a redifferentiation of its fibroblasts. During this modification (decidualization), the fibroblasts transform into large, polyhedral cells that establish ...
S.F. Oliveira, P. Abrahamsohn, T.M.T. Zorn   +2 more
doaj   +1 more source

Radiosynthesis and Preclinical Evaluation of an ¹⁸F-Labeled Triazolopyridopyrazine-Based Inhibitor for Neuroimaging of the Phosphodiesterase 2A (PDE2A)

Pharmaceuticals, 2022
The cyclic nucleotide phosphodiesterase 2A is an intracellular enzyme which hydrolyzes the secondary messengers cAMP and cGMP and therefore plays an important role in signaling cascades.
Barbara Wenzel, Stefan R. Fritzsche, Magali Toussaint, Detlef Briel, Klaus Kopka, Peter Brust, Matthias Scheunemann, Winnie Deuther-Conrad   +7 more
doaj   +1 more source

Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue

Acta Neuropathologica Communications, 2019
[F-18]-MK-6240, a novel tau positron emission tomography (PET) tracer recently discovered for the in vivo detection of neurofibrillary tangles, has the potential to improve diagnostic accuracy in the detection of Alzheimer disease.
Cinthya Aguero, M. Dhaynaut, M. Normandin, A. Amaral, N. Guehl, R. Neelamegam, M. Marquié, Keith A. Johnson, G. El Fakhri, M. Frosch, T. Gómez-Isla   +10 more
semanticscholar   +1 more source

Uranium Traps in Phreatic Sandstone-type Prospect, Taunsa Area, Dera Ghazi Khan, Eastern Sulaiman Range, Pakistan: Evidences from Autoradiography and Optical Microscopy

International Journal of Economic and Environment Geology, 2020
Taunsa uranium occurrence like other uranium resources in Pakistan is hosted by the Late Miocene-Pliocene age Litra Formation of the Siwalik Group molasse sediments.
Rahman Ullah, Nie Fengjuin, Zhang Xin, Zhang Chengyong, Asim Ali, Zhang Pengfei
doaj   +1 more source

Automated quantitative analysis of single and double label autoradiographs [PDF]

, 1979
A method for the analysis of silver grain content in both single and double label autoradiographs is presented. The total grain area is calculated by counting the number of pixels at which the recorded light intensity in transmission dark field ...
Aus, H. M., Harms, H., Haucke, M., Kellerer, Albrecht M., Korr, H., Maurer-Schultze, B., Meulen, V. ter, Ruter, A.   +7 more
core   +1 more source

[10] Whole-body autoradiography [PDF]

Journal of Histochemistry & Cytochemistry, 1981
Ever since its introduction in the early 1950s whole-body autoradiography has been used quite extensively for mapping the fate of various substances in the body, especially in the fields of pharmacology and toxicology. A detailed description of the whole-body autoradiographic technique is given.
Sven Ullberg, Bengt Larsson
openaire   +6 more sources

Cortical laminar tau deposits and activated astrocytes in Alzheimer’s disease visualised by 3H-THK5117 and 3H-deprenyl autoradiography

Scientific Reports, 2017
Hyperphosphorylated tau protein deposits and, inflammatory processes are characteristic components of Alzheimer disease (AD) pathology. We here aimed to visualize in vitro the distribution of tau deposits and activated astrocytes across the cortical ...
L. Lemoine, L. Saint‐Aubert, I. Nennesmo, P. Gillberg, A. Nordberg   +4 more
semanticscholar   +1 more source

In Vitro and In Vivo Characterization of Dibenzothiophene Derivatives [¹²⁵I]Iodo-ASEM and [¹⁸F]ASEM as Radiotracers of Homo- and Heteromeric α7 Nicotinic Acetylcholine Receptors

Molecules, 2020
The α7 nicotinic acetylcholine receptor (α7 nAChR) is involved in several cognitive and physiologic processes; its expression levels and patterns change in neurologic and psychiatric diseases, such as schizophrenia and Alzheimer’s disease,
Cornelius K. Donat, Henrik H. Hansen, Hanne D. Hansen, Ronnie C. Mease, Andrew G. Horti, Martin G. Pomper, Elina T. L’Estrade, Matthias M. Herth, Dan Peters, Gitte M. Knudsen, Jens D. Mikkelsen   +10 more
doaj   +1 more source

Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography [PDF]

, 2011
Accurate identification of ischemic penumbra will improve stroke patient selection for reperfusion therapies and clinical trials. Current magnetic resonance imaging (MRI) techniques have limitations and lack validation.
Barrie Condon, Celestine Santosh, Christopher McCabe, Craig A Robertson, I Mhairi Macrae, Keith W Muir, Kucinski T, Lindsay Gallagher, Maria del Rosario Lopez-Gonzalez, William M Holmes   +9 more
core   +1 more source

Combined [18F]DPA-714 micro-positron emission tomography and autoradiography imaging of microglia activation after closed head injury in mice

Journal of Neuroinflammation, 2016
BackgroundTraumatic brain injury (TBI) is a major cause of death and disability. Neuroinflammation contributes to acute damage after TBI and modulates long-term evolution of degenerative and regenerative responses to injury.
I. Israel, Andrea Ohsiek, E. Al‐Momani, C. Albert‐Weissenberger, C. Stetter, S. Mencl, A. Buck, C. Kleinschnitz, S. Samnick, A. Sirén   +9 more
semanticscholar   +1 more source