Results 51 to 60 of about 193,799 (312)

Amyloid-Targeting PET Tracer [18F]Flutemetamol Accumulates in Atherosclerotic Plaques

Molecules, 2019
Atherosclerosis is characterized by the accumulation of oxidized lipids in the artery wall, which triggers an inflammatory response. Oxidized low-density lipoprotein (ox-LDL) presents amyloid-like structural properties, and different amyloid species have
Sanna Hellberg, Johanna M.U. Silvola, Heidi Liljenbäck, Max Kiugel, Olli Eskola, Harri Hakovirta, Sohvi Hörkkö, Veronique Morisson-Iveson, Ella Hirani, Pekka Saukko, Seppo Ylä-Herttuala, Juhani Knuuti, Antti Saraste, Anne Roivainen   +13 more
doaj   +1 more source

Asymmetric Synthesis of Spirocyclic 2-Benzopyrans for Positron Emission Tomography of σ1 Receptors in the Brain

Pharmaceuticals, 2014
Sharpless asymmetric dihydroxylation of styrene derivative 6 afforded chiral triols (R)-7 and (S)-7, which were cyclized with tosyl chloride in the presence of Bu2SnO to provide 2-benzopyrans (R)-4 and (S)-4 with high regioselectivity.
Katharina Holl, Dirk Schepmann, Steffen Fischer, Friedrich-Alexander Ludwig, Achim Hiller, Cornelius K. Donat, Winnie Deuther-Conrad, Peter Brust, Bernhard Wünsch   +8 more
doaj   +1 more source

Noninvasive PET Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering [PDF]

, 2016
Transplantation of human muscle precursor cells (hMPCs) is envisioned for the treatment of various muscle diseases. However, a feasible noninvasive tool to monitor cell survival, migration, and integration into the host tissue is still missing. METHODS:
Ametamey, Simon M., Betzel, Thomas, Dinulovic, Ivana, Eberli, Daniel, Handschin, Christoph, Haralampieva, Deana, Krämer, Stefanie D., Salemi, Souzan, Schibli, Roger, Stoelting, Meline, Sulser, Tullio   +10 more
core   +2 more sources

In Vitro and In Vivo Characterization of Selected Fluorine-18 Labeled Radioligands for PET Imaging of the Dopamine D3 Receptor

Molecules, 2016
Cerebral dopamine D3 receptors seem to play a key role in the control of drug-seeking behavior. The imaging of their regional density with positron emission tomography (PET) could thus help in the exploration of the molecular basis of drug addiction.
Natascha Nebel, Simone Maschauer, Torsten Kuwert, Carsten Hocke, Olaf Prante   +4 more
doaj   +1 more source

Rabl's model of the interphase chromosome arrangement tested in Chinise hamster cells by premature chromosome condensation and laser-UV-microbeam experiments [PDF]

, 1982
In 1885 Carl Rabl published his theory on the internal structure of the interphase nucleus. We have tested two predictions of this theory in fibroblasts grown in vitro from a female Chinese hamster, namely (1) the Rabl-orientation of interphase ...
C Cremer, C Cremer, C Cremer, C Cremer, C Cremer, C Rabl, C Zorn, C Zorn, C. Cremer, C. Zorn, DE Comings, DE Comings, DM Pardoll, E. K. Luedtke, F Vogel, H Hoehn, H Zankl, H. Baumann, K Sperling, K Sperling, K Sperling, K. Sperling, KD Zang, L Avivi, L Hens, M Kirsch-Volders, M Kirsch-Volders, R Berezney, T Cremer, T. Cremer, Th Boveri, Th Boveri, V. Teuber, W Schnedl, Y Moroi   +34 more
core   +1 more source

64Cu-ATSM and 18FDG PET uptake and 64Cu-ATSM autoradiography in spontaneous canine tumors: comparison with pimonidazole hypoxia immunohistochemistry

Radiation Oncology, 2012
BackgroundThe aim of this study was to compare 64Cu-diacetyl-bis(N4-methylsemicarbazone) (64Cu-ATSM) and 18FDG PET uptake characteristics and 64Cu-ATSM autoradiography to pimonidazole immunohistochemistry in spontaneous canine sarcomas and carcinomas ...
A. E. Hansen, A. Kristensen, J. Jørgensen, F. McEvoy, M. Busk, A. J. van der Kogel, J. Bussink, S. Engelholm, A. Kjær   +8 more
semanticscholar   +1 more source

Liver regeneration in dogs: Morphologic and chemical changes [PDF]

, 1978
Forty-four percent and 72% hepatectomy were carried out in dogs and the animals were sacrificed for biochemical and pathologic studies from 0.5 to 6 days later.
Antonio Francavilla, Arthur F. Jones, Bucher, Bucher, Burton, Duguay, Faloona, Farivar, Fisher, Giles, Grisham, Harper, Herbert, Holley, Joseph Benichou, Kendrick A. Porter, Krishna, Leffert, Leffert, Loud, Lowry, MacManus, Makman, Moody, Price, Salomon, Schneider, Short, Starzl, Starzl, Starzl, Thomas E. Starzl, Weinbren, White, Whittemore   +34 more
core   +1 more source

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Proceedings of the National Academy of Sciences of the United States of America, 1979
A method has been devised for the electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. The method results in quantitative transfer of ribosomal proteins from gels containing urea.
H. Towbin, T. Staehelin, J. Gordon
semanticscholar   +1 more source

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84 [PDF]

, 1986
The localization of chromosome 18 in human interphase nuclei is demonstrated by use of radioactive and nonradioactive in situ hybridization techniques with a DNA clone designated L1.84.
A. Brückner, AHN Hopman, AL Jørgensen, AR Mitchell, B Trask, BU Zabel, CD Bloomfield, D Pinkel, GA Rappold, GA Rappold, H Hoehn, H. D. Hager, H. P. Scholl, HF Willard, J Wolfe, J. Landegent, JC Wu, JE Landegent, JE Landegent, L Manuelidis, LA Herzenberg, M Schardin, M Schmid, M Spaeter, M. Schardin, M. van der Ploeg, MM LeBeau, P Devilee, P Devilee, P. Devilee, P. Pearson, T Cremer, T. Cremer, W Schempp   +33 more
core   +1 more source

Phosphorylation of phosphoenolpyruvate carboxykinase in plants. Studies in plants with C4 photosynthesis and Crassulacean acid metabolism and in germinating seeds [PDF]

, 1996
We have previously shown that phosphoenolpyruvate carboxykinase (PEPCK) is phosphorylated in vivo in the cotyledons of darkened cucumber seedlings and that phosphorylation is reversed by light [Walker and Leegood (1995) FEBS Lett. 362, 70–74].
Leegood, R.C., Walker, R.P.
core