Results 81 to 90 of about 2,131 (168)

Additional file 2: of Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits [PDF]

, 2018
Autozygosity islands within the Nellore lineages by chromosome: Karvadi (red), Golias (Black), Godhavari (Green), Taj Mahal (blue), Akasamu (purple), and Nagpur (yellow).
Jason Osterstock (5754980), Fabieli Feitosa (3508652), Cláudio de Ulhoa Magnabosco (4476511), Sabrina Kluska (5754971), Elisa Peripolli (3508655), Mariana Berton (3508631), Fernando Di Croce (5754977), Angélica Pereira (3508634), Nedenia Stafuzza (3462848), Julia Metzger (149151), Marcos de Lemos (3508601), Sue Denise (5754983), Fernando Baldi (2833280), Danísio Munari (3407825), Bianca Olivieri (3508616), Fernando Lopes (559313), Raysildo Lôbo (5754974)   +16 more
core   +1 more source

Estimating Linkage Disequilibrium and Effective Population Size Across Generations in Holstein Cattle

Veterinary Medicine and Science, Volume 11, Issue 6, November 2025.
This study reveals a significant historical decline in effective population size (Ne) in Holstein cattle due to intensive breeding, with recent stabilization reflecting improved genetic management. Maintaining genetic diversity is vital for sustainable dairy cattle breeding programs.
Ronak Salehi, Arash Javanmard, Mahdi Mokhber, Sadegh Alijani   +3 more
wiley   +1 more source

Autozygome sequencing expands the horizon of human knockout research and provides novel insights into human phenotypic variation.

PLoS Genetics, 2013
The use of autozygosity as a mapping tool in the search for autosomal recessive disease genes is well established. We hypothesized that autozygosity not only unmasks the recessiveness of disease causing variants, but can also reveal natural knockouts of ...
Ahmed B Alsalem, Anason S Halees, Shamsa Anazi, Shomoukh Alshamekh, Fowzan S Alkuraya   +4 more
doaj   +1 more source

Application of genome-wide single nucleotide polymorphism typing: simple association and beyond. [PDF]

PLoS Genetics, 2006
The International HapMap Project and the arrival of technologies that type more than 100,000 SNPs in a single experiment have made genome-wide single nucleotide polymorphism (GW-SNP) assay a realistic endeavor.
J Raphael Gibbs, Andrew Singleton
doaj   +1 more source

High Imputation Accuracy Can Be Achieved Using a Small Reference Panel in a Natural Population With Low Genetic Diversity

Molecular Ecology Resources, Volume 25, Issue 8, November 2025.
ABSTRACT Genotype imputation, the inference of missing genotypes using a reference set of population haplotypes, is a cost‐effective tool for improving the quality and quantity of genetic datasets. Imputation is usually applied to large and well‐characterised datasets of humans and livestock, even though it could also benefit smaller natural ...
Hui Zhen Tan, Katarina C. Stuart, Tram Vi, Annabel Whibley, Sarah Bailey, Patricia Brekke, Anna W. Santure   +6 more
wiley   +1 more source

A post‐translocation genetic analysis of an endemic wingless grasshopper in urban environments

Conservation Science and Practice, Volume 7, Issue 10, October 2025.
Translocations are increasingly used in conservation, yet invertebrate outcomes remain understudied. This study assessed genetic diversity in a recently translocated flightless grasshopper (Vandiemenella viatica), finding declines in heterozygosity and nucleotide diversity, alongside increased homozygosity in the F2 generation.
Hiromi Yagui, Michael R. Kearney, Thomas L. Schmidt, Ary A. Hoffmann   +3 more
wiley   +1 more source

Additional file 7: of Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits [PDF]

, 2018
Gene Ontology terms annotation analysis enriched (P 
Jason Osterstock (5754980), Fabieli Feitosa (3508652), Cláudio de Ulhoa Magnabosco (4476511), Sabrina Kluska (5754971), Elisa Peripolli (3508655), Mariana Berton (3508631), Fernando Di Croce (5754977), Angélica Pereira (3508634), Nedenia Stafuzza (3462848), Julia Metzger (149151), Marcos de Lemos (3508601), Sue Denise (5754983), Fernando Baldi (2833280), Danísio Munari (3407825), Bianca Olivieri (3508616), Fernando Lopes (559313), Raysildo Lôbo (5754974)   +16 more
core   +1 more source

Age-based partitioning of individual genomic inbreeding levels in Belgian Blue cattle

Genetics Selection Evolution, 2017
Background Inbreeding coefficients can be estimated either from pedigree data or from genomic data, and with genomic data, they are either global or local (when the linkage map is used).
Marina Solé, Ann-Stephan Gori, Pierre Faux, Amandine Bertrand, Frédéric Farnir, Mathieu Gautier, Tom Druet   +6 more
doaj   +1 more source

Estimation of Inbreeding Depression From Overdominant Loci Using Molecular Markers

Evolutionary Applications, Volume 18, Issue 3, March 2025.
ABSTRACT Inbreeding depression is a highly relevant universal phenomenon in population and conservation genetics since it leads to a decline in the fitness of individuals. This phenomenon is due to the homozygous expression of alleles whose effects are hidden in heterozygotes (inbreeding load).
Inés González‐Castellano, Pilar Ordás, Armando Caballero   +2 more
wiley   +1 more source

Genomic Diversity as a Key Conservation Criterion: Proof‐of‐Concept From Mammalian Whole‐Genome Resequencing Data

Evolutionary Applications
Many international, national, state, and local organizations prioritize the ranking of threatened and endangered species to help direct conservation efforts. For example, the International Union for Conservation of Nature (IUCN) assesses the Green Status
Jong Yoon Jeon, Andrew N. Black, Erangi J. Heenkenda, Andrew J. Mularo, Gina F. Lamka, Safia Janjua, Anna Brüniche‐Olsen, John W. Bickham, Janna R. Willoughby, J. Andrew DeWoody   +9 more
doaj   +1 more source