Results 71 to 80 of about 1,564 (152)

Genomic insights into the population structure and genetic diversity of Ugandan indigenous cattle

Animal Genetics, Volume 56, Issue 6, December 2025.
Abstract Domestic cattle in Africa can be categorized as either taurine (Bos taurus) or indicine (Bos indicus) based on their domestication histories from the extinct aurochs (Bos primigenius). Close to 150 breeds of indigenous cattle are estimated to exist in Africa and have a complex mixture of B. taurus and B. indicus ancestries.
Rodney Okwasiimire, Donald R. Kugonza, Daniil Ruvinskiy, Melak Weldenegodguad, Nasser Ghanem, Mahlako L. Makgahlela, Catarina Ginja, Richard P. M. A. Crooijmans, Juha Kantanen, Pekka Uimari, Kisun Pokharel   +10 more
wiley   +1 more source

Population Genomics of Incipient Allochronic Divergence in the Pine Processionary Moth

Molecular Ecology, Volume 34, Issue 24, December 2025.
ABSTRACT Allochronic divergence is a key evolutionary mechanism that can frequently lead to incipient speciation. Although theoretical models suggest that such divergence is notably facilitated by small population size and genetic polymorphisms influencing reproductive timing, though constrained by genetic load, empirical validation remains limited. We
Tanguy Muller, Mathieu Gautier, Éric Lombaert, Raphaël Leblois, Laure Sauné, Manuela Branco, Carole Kerdelhué, Charles Perrier   +7 more
wiley   +1 more source

Estimating Linkage Disequilibrium and Effective Population Size Across Generations in Holstein Cattle

Veterinary Medicine and Science, Volume 11, Issue 6, November 2025.
This study reveals a significant historical decline in effective population size (Ne) in Holstein cattle due to intensive breeding, with recent stabilization reflecting improved genetic management. Maintaining genetic diversity is vital for sustainable dairy cattle breeding programs.
Ronak Salehi, Arash Javanmard, Mahdi Mokhber, Sadegh Alijani   +3 more
wiley   +1 more source

Age-based partitioning of individual genomic inbreeding levels in Belgian Blue cattle

Genetics Selection Evolution, 2017
Background Inbreeding coefficients can be estimated either from pedigree data or from genomic data, and with genomic data, they are either global or local (when the linkage map is used).
Marina Solé, Ann-Stephan Gori, Pierre Faux, Amandine Bertrand, Frédéric Farnir, Mathieu Gautier, Tom Druet   +6 more
doaj   +1 more source

High Imputation Accuracy Can Be Achieved Using a Small Reference Panel in a Natural Population With Low Genetic Diversity

Molecular Ecology Resources, Volume 25, Issue 8, November 2025.
ABSTRACT Genotype imputation, the inference of missing genotypes using a reference set of population haplotypes, is a cost‐effective tool for improving the quality and quantity of genetic datasets. Imputation is usually applied to large and well‐characterised datasets of humans and livestock, even though it could also benefit smaller natural ...
Hui Zhen Tan, Katarina C. Stuart, Tram Vi, Annabel Whibley, Sarah Bailey, Patricia Brekke, Anna W. Santure   +6 more
wiley   +1 more source

Genomic Diversity as a Key Conservation Criterion: Proof‐of‐Concept From Mammalian Whole‐Genome Resequencing Data

Evolutionary Applications
Many international, national, state, and local organizations prioritize the ranking of threatened and endangered species to help direct conservation efforts. For example, the International Union for Conservation of Nature (IUCN) assesses the Green Status
Jong Yoon Jeon, Andrew N. Black, Erangi J. Heenkenda, Andrew J. Mularo, Gina F. Lamka, Safia Janjua, Anna Brüniche‐Olsen, John W. Bickham, Janna R. Willoughby, J. Andrew DeWoody   +9 more
doaj   +1 more source

Genotype-phenotype correlation and description of two novel mutations in Iranian patients with glycogen storage disease 1b (GSD1b)

Orphanet Journal of Rare Diseases, 2020
Background Glycogen storage disease (GSD) is a rare inborn error of the synthesis or degradation of glycogen metabolism. GSD1, the most common type of GSD, is categorized into GSD1a and GSD1b which caused by the deficiency of glucose-6-phosphatase (G6PC)
Maryam Eghbali, Maryam Abiri, Saeed Talebi, Zahra Noroozi, Marjan Shakiba, Parastoo Rostami, Hosein Alimadadi, Mehri Najafi, Fatemeh Yazarlou, Ali Rabbani, Mohammad Hossein Modarressi   +10 more
doaj   +1 more source

A post‐translocation genetic analysis of an endemic wingless grasshopper in urban environments

Conservation Science and Practice, Volume 7, Issue 10, October 2025.
Translocations are increasingly used in conservation, yet invertebrate outcomes remain understudied. This study assessed genetic diversity in a recently translocated flightless grasshopper (Vandiemenella viatica), finding declines in heterozygosity and nucleotide diversity, alongside increased homozygosity in the F2 generation.
Hiromi Yagui, Michael R. Kearney, Thomas L. Schmidt, Ary A. Hoffmann   +3 more
wiley   +1 more source

Clinical applications of Genome Polymorphism Scans

Biology Direct, 2006
Applications of Genome Polymorphism Scans range from the relatively simple such as gender determination and confirmation of biological relationships, to the relatively complex such as determination of autozygosity and propagation of genetic information ...
Weber James L
doaj   +1 more source

No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study.

PLoS Genetics, 2016
It is well known that inbreeding increases the risk of recessive monogenic diseases, but it is less certain whether it contributes to the etiology of complex diseases such as schizophrenia.
Emma C Johnson, Douglas W Bjelland, Daniel P Howrigan, Abdel Abdellaoui, Gerome Breen, Anders Borglum, Sven Cichon, Franziska Degenhardt, Andreas J Forstner, Josef Frank, Giulio Genovese, Stefanie Heilmann-Heimbach, Stefan Herms, Per Hoffman, Wolfgang Maier, Manuel Mattheisen, Derek Morris, Bryan Mowry, Betram Müller-Mhysok, Benjamin Neale, Igor Nenadic, Markus M Nöthen, Colm O'Dushlaine, Marcella Rietschel, Douglas M Ruderfer, Dan Rujescu, Thomas G Schulze, Matthew A Simonson, Eli Stahl, Jana Strohmaier, Stephanie H Witt, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Patrick F Sullivan, Matthew C Keller   +33 more
doaj   +1 more source