Results 51 to 60 of about 2,131 (168)

Additional file 3: of Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits [PDF]

, 2018
Overlapping autozygosity islands within the Nellore lineages.
Jason Osterstock (5754980), Fabieli Feitosa (3508652), Cláudio de Ulhoa Magnabosco (4476511), Sabrina Kluska (5754971), Elisa Peripolli (3508655), Mariana Berton (3508631), Fernando Di Croce (5754977), Angélica Pereira (3508634), Nedenia Stafuzza (3462848), Julia Metzger (149151), Marcos de Lemos (3508601), Sue Denise (5754983), Fernando Baldi (2833280), Danísio Munari (3407825), Bianca Olivieri (3508616), Fernando Lopes (559313), Raysildo Lôbo (5754974)   +16 more
core   +1 more source

Runs of homozygosity for autozygosity estimation and genomic analysis in production animals [PDF]

Pesquisa Agropecuária Brasileira, 2018
: Runs of homozygosity (ROHs) are long stretches of homozygous genomic segments, identifiable by molecular markers, which can provide genomic information for accurate estimates to characterize populations, determine evolutionary history and demographic ...
Arnaldo Basso Rebelato, Alexandre Rodrigues Caetano   +1 more
doaj   +3 more sources

“Assessing the Impact of Individual Autozygosity on Complex Traits”

, 2022
Abstract Autozygosity, the proportion of the genome that is homozygous by descent, has been associated with variation in multiple health-related traits impacting evolutionary fitness. Autozygosity (FROH) is typically measured from runs of homozygosity (ROHs) that arise when identical-by-descent (IBD) haplotypes are inherited from each parent ...
Megan T. Lynch, Kristin A. Maloney, Huichun Xu, James A. Perry, Alan R. Shuldiner, Braxton D. Mitchell, Regeneron Genetics Center N/A   +6 more
openaire   +1 more source

Lack of involvement of known DNA methyltransferases in familial hydatidiform mole implies the involvement of other factors in establishment of imprinting in the human female germline

BMC Genetics, 2003
Background Differential methylation of the two alleles is a hallmark of imprinted genes. Correspondingly, loss of DNA methyltransferase function results in aberrant imprinting and abnormal post-fertilization development.
Picton H M, Huntriss J, Hodge D, Judson H, De Vos M, Hayward B E, Sheridan E, Bonthron DT   +7 more
doaj   +1 more source

Additional file 2 of Associations of genome-wide and regional autozygosity with 96 complex traits in old order Amish [PDF]

, 2023
Additional file 2: Supplemental Table 1. "Panel of complex traits measured in Amish participants that were tested for association with regional and global autozygosity." - this title is incorrect in the current ...
Kristin A. Maloney (12647776), James A. Perry (10515389), Megan T. Lynch (15265802), Braxton D. Mitchell (7703402), Huichun Xu (48283), Regeneron Genetics Center (13904802), Alan R. Shuldiner (12258643)   +6 more
core   +1 more source

Locating a novel autosomal recessive genetic variant in the cattle glucokinase gene using only WGS data from three cases and six carriers

Frontiers in Genetics, 2022
New Mendelian genetic conditions, which adversely affect livestock, arise all the time. To manage them effectively, some methods need to be devised that are quick and accurate.
Geoffrey E. Pollott, Richard J. Piercy, Claire Massey, Mazdak Salavati, Mazdak Salavati, Zhangrui Cheng, D. Claire Wathes   +6 more
doaj   +1 more source

Mapping of homozygosity and autozygosity for skeletal dysplasia. [PDF]

, 2015
(A) The results of the genome-wide homozygosity and autozygosity mapping of skeletal dysplasia using 14 affected and 34 normal animals from three families. Black horizontal bars mark the limits between the 29 autosomes.
Naoto Watanabe (384447), Tamako Matsuhashi (414232), Hiroshi Okabe (273882), Takashi Hirano (414231), Tatsuo Fujita (787341), Makio Hayakawa (787342), Kunio Sato (787335), Akio Suzuki (624761), Takatoshi Kojima (787343), Toshitake Ootsubo (787340), Hiroshi Kobayashi (23858), Ichiro Tabuchi (4742), Shota Nishimura (238266), Takehito Tsuji (787338), Yoshikazu Sugimoto (151140), Yosuke Saito (787337), Shinji Sasaki (238265), Akiko Takasuga (414234), Toshio Watanabe (151136), Koji Setoguchi (787339), Ryouichi Nakamura (787336)   +20 more
core   +1 more source

Genome-Wide Runs of Homozygosity Revealed Selection Signatures in Bos indicus

Frontiers in Genetics, 2020
Genome-wide runs of homozygosity (ROH) are suitable for understanding population history, calculating genomic inbreeding, deciphering genetic architecture of complex traits and diseases as well as identifying genes linked with agro-economic traits ...
S. P. Dixit, Sanjeev Singh, Indrajit Ganguly, Avnish Kumar Bhatia, Anurodh Sharma, N. Anand Kumar, Ajay Kumar Dang, S. Jayakumar   +7 more
doaj   +1 more source

Comparative evaluation of genomic inbreeding parameters in seven commercial and autochthonous pig breeds

Animal, 2020
Single nucleotide polymorphism (SNP) genotyping tools, which can analyse thousands of SNPs covering the whole genome, have opened new opportunities to estimate the inbreeding level of animals directly using genome information.
G. Schiavo, S. Bovo, F. Bertolini, S. Tinarelli, S. Dall’Olio, L. Nanni Costa, M. Gallo, L. Fontanesi   +7 more
doaj   +1 more source

Additional file 1: of Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits [PDF]

, 2018
Autozygosity islands across the Nellore cattle genome.
Jason Osterstock (5754980), Fabieli Feitosa (3508652), Cláudio de Ulhoa Magnabosco (4476511), Sabrina Kluska (5754971), Elisa Peripolli (3508655), Mariana Berton (3508631), Fernando Di Croce (5754977), Angélica Pereira (3508634), Nedenia Stafuzza (3462848), Julia Metzger (149151), Marcos de Lemos (3508601), Sue Denise (5754983), Fernando Baldi (2833280), Danísio Munari (3407825), Bianca Olivieri (3508616), Fernando Lopes (559313), Raysildo Lôbo (5754974)   +16 more
core   +1 more source