Results 51 to 60 of about 1,564 (152)
Advanced Science, Volume 13, Issue 42, 28 July 2026.Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao +7 more
wiley +1 more source
Molecular Ecology Resources, Volume 26, Issue 5, July 2026.ABSTRACT Low‐coverage whole‐genome sequencing (lcWGS) combined with genotype imputation is increasingly being used to generate large genomic datasets at reduced cost, offering a promising alternative for conservation genomics. Here, we use the Iberian lynx (Lynx pardinus), a species with extremely low genetic diversity, genetically differentiated ...
Lucía Mayor‐Fidalgo +4 more
wiley +1 more source
Runs of Homozygosity as Footprints of Selection in the Norik of Muran Horse Genome
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2019 The aim of this study was to analyse the genome-wide distribution of runs of homozygosity (ROH) segments in the genome of Norik of Muran horse and to identify the regions under strong selection pressure. Overall, 25 animals genotyped by the GGP Equine70k
Nina Moravčíková +5 more
doaj +1 more source
Conservation Status of Two Italian Local Poultry Breeds: Faraona Camosciata and Oca Padovana
Animal Genetics, Volume 57, Issue 3, June 2026.ABSTRACT The present study aimed to assess the conservation status and characterize the phenotypic and genomic diversity of two endangered Italian poultry genetic resources to guide their conservation plans. Blood samples and morphometric data were collected on 50 Faraona Camosciata (FAC, Numida meleagris) and 50 Oca Padovana (OPD, Anser anser) adult ...
Filippo Cendron +7 more
wiley +1 more source
Autozygosity Mapping of a Seckel Syndrome Locus to Chromosome 3q22.1-q24 [PDF]
The American Journal of Human Genetics, 2000 Seckel syndrome (MIM 210600) is an autosomal recessive disorder of low birth weight, severe microcephaly, and dysmorphic facial appearance with receding forehead, prominent nose, and micrognathia. We have performed a genomic screen in two consanguineous families of Pakistani origin and found that the disorder segregates with markers between loci ...
Goodship, Judith +5 more
openaire +3 more sources
KinSNP software for homozygosity mapping of disease genes using SNP microarrays
Human Genomics, 2010 Consanguineous families affected with a recessive genetic disease caused by homozygotisation of a mutation offer a unique advantage for positional cloning of rare diseases.
Amir El-Ad +6 more
doaj +1 more source
Nature Communications, 2020 The prevalence of cardiometabolic diseases (CMDs) is increasing rapidly across Africa. Here, the authors investigate autozygosity in CMD-associated traits in over 10,000 sub-Saharan African individuals, showing these traits are influenced by sex-specific
Francisco C. Ceballos +10 more
doaj +1 more source
Molecular Ecology, Volume 35, Issue 8, April 2026.ABSTRACT Species distributed across heterogeneous environments often evolve locally adapted populations, but understanding how these persist in the presence of homogenizing gene flow remains puzzling. In Gabon, Anopheles coluzzii, a major African malaria mosquito, is found in various ecological settings, including urban areas, remote rural villages ...
Josquin Daron +12 more
wiley +1 more source
Autozygosity mapping of Bardet–Biedl syndrome to 12q21.2 and confirmation of FLJ23560 as BBS10 [PDF]
European Journal of Human Genetics, 2006 Bardet-Biedl syndrome (BBS) is a genetically heterogeneous autosomal recessive disorder characterized by variable obesity, pigmentary retinopathy, polydactyly, mental retardation, hypogonadism and renal failure. In order to identify novel BBS loci we undertook autozygosity mapping studies using high-density SNP microarrays in consanguineous kindreds ...
White, DRE +15 more
openaire +3 more sources
Effects of autozygosity and schizophrenia polygenic risk on cognitive and brain developmental trajectories [PDF]
European Journal of Human Genetics, 2017 ABSTRACT Cognitive and brain development are determined by dynamic interactions between genes and environment across the lifespan. Aside from marker-by-marker analyses of polymorphisms, biologically meaningful features of the whole-genome (derived from the combined effect of individual markers) have been postulated to inform on human ...
Aldo Córdova-Palomera +11 more
openaire +2 more sources