Results 61 to 70 of about 2,455 (150)
Molecular Ecology, Volume 35, Issue 8, April 2026.ABSTRACT Species distributed across heterogeneous environments often evolve locally adapted populations, but understanding how these persist in the presence of homogenizing gene flow remains puzzling. In Gabon, Anopheles coluzzii, a major African malaria mosquito, is found in various ecological settings, including urban areas, remote rural villages ...
Josquin Daron +12 more
wiley +1 more source
, 2023 Additional file 2: Supplemental Table 1. "Panel of complex traits measured in Amish participants that were tested for association with regional and global autozygosity." - this title is incorrect in the current ...
Kristin A. Maloney (12647776) +6 more
core +1 more source
Application of genome-wide single nucleotide polymorphism typing: simple association and beyond. [PDF]
PLoS Genetics, 2006 The International HapMap Project and the arrival of technologies that type more than 100,000 SNPs in a single experiment have made genome-wide single nucleotide polymorphism (GW-SNP) assay a realistic endeavor.
J Raphael Gibbs, Andrew Singleton
doaj +1 more source
BMC Genomics, 2018 Background While autozygosity as a consequence of selection is well understood, there is limited information on the ability of different methods to measure true inbreeding.
Mehrnush Forutan +5 more
doaj +1 more source
PLoS Genetics, 2013 The use of autozygosity as a mapping tool in the search for autosomal recessive disease genes is well established. We hypothesized that autozygosity not only unmasks the recessiveness of disease causing variants, but can also reveal natural knockouts of ...
Ahmed B Alsalem +4 more
doaj +1 more source
Mapping of homozygosity and autozygosity for skeletal dysplasia.
, 2015 (A) The results of the genome-wide homozygosity and autozygosity mapping of skeletal dysplasia using 14 affected and 34 normal animals from three families. Black horizontal bars mark the limits between the 29 autosomes.
Naoto Watanabe (384447) +20 more
core +1 more source
Accurate Runs of Homozygosity Estimation From Low Coverage Genome Sequences in Non‐Model Species
Molecular Ecology Resources, Volume 26, Issue 1, January 2026.ABSTRACT Runs of homozygosity (ROH) are increasingly being analysed using whole genome sequences in non‐model species as a measure of inbreeding and to assess demographic history, thus providing useful information for conservation. However, most studies have used Plink for ROH inference which performs poorly when sequencing depth is below 10×, often ...
Rebecca S. Taylor +2 more
wiley +1 more source
, 2018 Autozygosity islands across the Nellore cattle genome.
Jason Osterstock (5754980) +16 more
core +1 more source
Molecular Ecology, Volume 35, Issue 2, January 2026.ABSTRACT Conservation management of endangered species increasingly relies on genomic approaches to understand how long‐term small population sizes affect the fitness of extant individuals. However, despite the growing investment in genomic resources by conservation programmes, the impact that sequencing methods have on the ability to detect inbreeding‐
Yasmin Foster +12 more
wiley +1 more source
Coexisting ADAR and TSHB Mutations in an Infant With Retinal Detachment and Transient Cardiomyopathy
Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.Background Central congenital hypothyroidism (C‐CH) due to thyroid‐stimulating hormone beta (TSHB) variants is rare and often missed by thyroid‐stimulating hormone (TSH)–based neonatal screening. Adenosine deaminase acting on RNA (ADAR)‐related Aicardi–Goutières syndrome type 6 (AGS6) is an interferonopathy with early‐onset encephalopathy.
Tamer Draidi +5 more
wiley +1 more source