Results 121 to 130 of about 1,112,329 (254)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Normal background concentrations of contaminants in the soils of England : available data and data exploration [PDF]

, 2011
This draft report describes the completed Work Package 1 and 2 tasks of the Defra commissioned Science and Research Project SP1008 - Establishing data on normal/background levels of soil contamination in England.
Ander, E.L., Cave, M.R., Johnson, C.C., Palumbo-Roe, B.   +3 more
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Temporal and spatial variability in availability bias has consequences for marine bird abundance estimates during the non‐breeding season

Ecological Solutions and Evidence
To effectively monitor how marine ecosystems are being reshaped by anthropogenic pressures, we require understanding of species abundances and distributions.
Ruth E. Dunn, James Duckworth, Susan O'Brien, Robert W. Furness, Lila Buckingham, Francis Daunt, Maria Bogdanova, Jonathan A. Green   +7 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

The Availability Trap: How the Availability Bias and Fitness Influencers Mould Followers’ Behaviour

International Journal For Multidisciplinary Research
The advent of social media has opened up a gateway of opportunities to provide people with information and means to a healthier lifestyle. However, due to this, there has also been a change in what people consider to be “normal”. With social media apps like Instagram and TikTok, people fall prey to the “Availability Bias” in which individuals rely on ...
Ammar Lokhandwala -, Govind Shastri -, Aruna P -   +2 more
openaire   +1 more source

Returns to Schooling in Spain. How Reliable Are IV Estimates? [PDF]

This paper studies the Ordinary Least-Squared (OLS) and Instrumental Variables (IV) estimates of the returns to schooling for male workers in Spain.
Empar Pons, Maria Teresa Gonzalo
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Availability Heuristic Will Affect Decision-making and Result in Bias

DEStech Transactions on Social Science, Education and Human Science, 2017
Heuristic is a strategy that allows us to make decision without complicate information gathering and analyzing. Availability heuristic is a type of heuristic that concentrates on retrieving information from memory. However, there are four factors that may induce bias from the use of availability heuristic.
openaire   +2 more sources

Revealed Preferences, Choices, and Psychological Indexes [PDF]

This paper develops a model of choice that embeds some psychological aspects affecting decision maker's behaviour. In the model, the decision maker attaches an unobservable psychological index -representing, e.g., the level of perceived availability or ...
Ivan Soraperra
core