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Further insight into the bioactivity of the freshwater sponge Ochridaspongia rotunda. [PDF]
Pharm Biol, 2017 Talevska A +3 more
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A focused library synthesis and cytotoxicity of quinones derived from the natural product bolinaquinone. [PDF]
R Soc Open Sci, 2018 Ghods A +5 more
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Antifungal effects of ethanolic and aqueous extracts of Vitexagnus-castus against vaginal isolates of Candida albicans. [PDF]
Curr Med Mycol, 2018 Keikha N +4 more
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Enantioselective Total Synthesis of Avarol and Avarone
Angewandte Chemie International Edition, 1999Formation of the C11-C1' bond through application of Barton's radical decarboxylation and quinone addition is the cornerstone of a new convergent and concise synthesis of the marine metabolites avarol (1) and avarone (2; see scheme), for which antimitotic, antileukemic, and antiviral effects have been reported.
, Ling, , Xiang, , Theodorakis
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Stereoselective Synthesis of (+)-Avarol, (+)-Avarone, and Some Nonracemic Analogues
The Journal of Organic Chemistry, 1996Synthesis of the rearranged drimane sesquiterpenoids (+)-avarol and (+)-avarone from Wieland-Miescher ketone is described. This synthetic sequence provides convenient access to the natural enantiomers and, based on comparison of the optical rotation of synthetic avarol dimethyl ether with literature data, affords material of significantly higher ...
Jianguo, An, David F., Wiemer
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Antibacterial and Antifungal Activity of Avarone and Avarol
Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology, 1985The sesquiterpenoid hydroquinone and quinone, Avarol and Avarone, were previously found to be potent antitumor agents (Müller et al., 1984). In the present study it is reported that in aqueous solution (pH 7.2), in the presence of dimethylsulfoxide, Avarol is converted to Avarone.
G, Seibert +5 more
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Antimutagenic activity of the novel antileukemic agents, avarone and avarol
Mutation Research Letters, 1985The two antileukemic agents, avarone and avarol, were determined to be neither direct nor indirect mutagenic agents in the Ames microsomal test. Moreover, the two sesquiterpenoid compounds drastically reduced the mutagenic effect of benzo[a]pyrene in the same system.
B, Kurelec +5 more
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