Avenanthramide-C reduces the viability of MDA-MB-231 breast cancer cells through an apoptotic mechanism [PDF]
Cancer Cell International, 2017 Background Avenanthramides (AVN) are a relatively unstudied family of phytochemicals that could be novel chemotherapeutics. These compounds, found in oats, are non-toxic to healthy cells and have been shown to reduce viability of human colon and liver ...
Jordan Hastings, Jason Kenealey
doaj +5 more sources
Avenanthramide-C ameliorate doxorubicin-induced hepatotoxicity via modulating Akt/GSK-3β and Wnt-4/β-Catenin pathways in male rats [PDF]
Frontiers in Molecular BiosciencesBackgroundDoxorubicin (DOX) drugs used in cancer treatment can cause various adverse effects, including hepatotoxicity. Natural-derived constituents have shown promising effects in alleviating chemotherapy-induced toxicities.
Maha Abdullah Alwaili +11 more
doaj +4 more sources
Corrigendum: Avenanthramide-C ameliorate doxorubicin-induced hepatotoxicity via modulating Akt/GSK-3β and Wnt-4/β-Catenin pathways in male rats [PDF]
Frontiers in Molecular BiosciencesMaha Abdullah Alwaili +11 more
doaj +3 more sources
Diversity of avenanthramide content in wild and cultivated oats [PDF]
Труды по прикладной ботанике, генетике и селекции, 2020 Background. Oat grains accumulate substantial amounts of various phenolic compounds that possess biological activity and have a potential to considerably increase health benefits of oats as a food.
S. Leonova +5 more
doaj +3 more sources
Exploring Nutritional Quality and Bioactive Compounds in Oat Mediterranean Landraces and Cultivars [PDF]
AntioxidantsOat (Avena sativa L.) is increasingly recognized as a functional food due to its unique profile of antioxidant and health-promoting compounds. Beyond its traditional role, our study reveals that Mediterranean landraces and related species harbour ...
Elena Prats +5 more
doaj +2 more sources
Oat-based milk alternatives: the influence of physical and chemical properties on the sensory profile. [PDF]
Front NutrOat-based milk alternatives (OMAs) have become increasingly popular, perhaps due to their low allergenicity and preferred sensory attributes when compared to other milk alternatives.
McCarron R +4 more
europepmc +3 more sources
Avenanthramide-C Shows Potential to Alleviate Gingival Inflammation and Alveolar Bone Loss in Experimental Periodontitis. [PDF]
Mol Cells, 2023 Periodontal disease is a chronic inflammatory disease that leads to the gradual destruction of the supporting structures of the teeth including gums, periodontal ligaments, alveolar bone, and root cementum. Recently, interests in alleviating symptoms of periodontitis (PD) using natural compounds is increasing.
Kim SJ +8 more
europepmc +3 more sources
Synthesis of Avenanthramide C and Its Analogs Utilizing Classical Condensation, Saponification and Acidification [PDF]
ACS OmegaSe Myeong Choi +5 more
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Protective Effect of Avenanthramide-C on Auditory Hair Cells against Oxidative Stress, Inflammatory Cytokines, and DNA Damage in Cisplatin-Induced Ototoxicity. [PDF]
Int J Mol Sci, 2023 Cisplatin-induced ototoxicity leads to hearing impairment, possibly through reactive oxygen species (ROS) production and DNA damage in cochlear hair cells (HC), although the exact mechanism is unknown. Avenanthramide-C (AVN-C), a natural, potent antioxidant, was evaluated in three study groups of normal adult C57Bl/6 mice (control, cisplatin, and AVN-C+
Umugire A +7 more
europepmc +3 more sources
Avenanthramide C From Oats Possibly Exerts Anti-Inflammatory Effects in Human Umbilical Vein Endothelial Cells. [PDF]
J Food SciABSTRACT Chronic kidney disease (CKD) is associated with inflammation and cardiovascular complications and is partly exacerbated by the uremic toxin indoxyl sulfate (IS). IS is known to activate the aryl hydrocarbon receptor (AhR) to promote vascular inflammation.
Sasaki H +8 more
europepmc +2 more sources