Avenanthramide C from germinated oats exhibits anti-allergic inflammatory effects in mast cells. [PDF]
Sci Rep, 2019 AbstractMast cells play a crucial role in allergic diseases via the release of inflammatory mediators, particularly histamine and pro-inflammatory cytokines. Avenanthramide (Avn) C, a polyphenol found mainly in oats, is known to exhibit various biological properties.
Dhakal H +11 more
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Avenanthramide-C prevents noise- and drug-induced hearing loss while protecting auditory hair cells from oxidative stress. [PDF]
Cell Death Discov, 2019 AbstractNoise exposure or ototoxic drugs instigate various types of damage to the cochlea, resulting in hearing loss (HL). While the incidence of HL is growing continuously, there are, so far, no adequate drugs to prevent or treat HL. Avenanthramide (AVN), a natural product extracted from oats, has been reported to possess anti-oxidant/inflammatory ...
Umugire A +5 more
europepmc +4 more sources
Avenanthramide-C Mitigates High-Fat Diet-Accelerated Alzheimer's Pathologies via NOD1-Driven Neuroinflammation in 5×FAD Mice. [PDF]
NutrientsBackground: Obesity is clinically known to be associated with an increased risk and aggravated pathology of Alzheimer’s disease (AD). A high-fat diet (HFD), the major contributor to obesity, induces neuroinflammation and central insulin resistance, both of which are linked to synaptic dysfunction. Our previous studies demonstrated that avenanthramide-C
Wang M, Jin B, Xu J, Wang C.
europepmc +3 more sources
Materials Today Bio, 2022 Chemodynamic therapy (CDT) is a promising tumor-specific treatment, but still suffering insufficient reactive oxygen species (ROS) levels due to its limited efficacy of Fenton/Fenton-like reaction.
Huijia Mao +5 more
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Ferulic acid derivatives and avenanthramides modulate endothelial function through maintenance of nitric oxide balance in huvec cells [PDF]
, 2021 Wholegrain oats contain a variety of phenolic compounds thought to help maintain healthy vascular function, through the maintenance of local levels of the vasodilator nitric oxide (NO). Thus, the full molecular mechanisms involved are not yet clear. With
Corona G. +8 more
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Action Mechanisms of Small Extracellular Vesicles in Inflammaging [Review] [PDF]
, 2022 This article belongs to the Special Issue Extracellular Vesicles Research in Inflamm-Aging[Abstract] The accumulation process of proinflammatory components in the body due to aging influences intercellular communication and is known as inflammaging. This
Alarcón-Veleiro, Carmen +10 more
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Shenxiong Drop Pill exerts neuroprotective effect against focal cerebral ischemia partly via regulation of the expressions of ICAM-1 and caspase-3 [PDF]
, 2021 Purpose: To investigate the effect of Shenxiong Drop Pill (SXDP) on cerebral infarction (CI) in rats, and the involvement of anti-inflammatory response in the process.Methods: Rats were sacrificed at three different time points, viz, 24, 48 and 72 h ...
Chen, Wei-yin +8 more
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Computational study, synthesis and evaluation of active peptides derived from Parasporin-2 and spike protein from Alphacoronavirus against colon cancer cells [PDF]
, 2021 Parasporin-2Aa1 (PS2Aa1) is a toxic protein of 37 KDa (30 kDa, activated form produced by proteolysis) that was shown to be cytotoxic against specific human cancer cells, although its mechanism of action has not been elucidated yet. In order to study the
Cruz, Jenniffer +6 more
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Frontiers in Nutrition, 2021 Background: Oat and its compounds have been found to have anti-inflammatory effects. Through this systematic review and meta-analysis, we aimed to determine an evidence-based link between oat consumption and inflammatory markers.Methods: The Preferred ...
Sun Jo Kim +7 more
doaj +1 more source
Effects of Cultivar on Phenolic Content and Antioxidant Activity of Naked Oat in China
Journal of Integrative Agriculture, 2014 To evaluate the effects of naked oat cultivars on their phenolic contents and antioxidant activities, the oat seeds from 21 different cultivars in China were collected, and their major nutritional components, compositions of polyphenols, and antioxidant ...
Li-tao TONG +5 more
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