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Antioxidant Effects of Oats Avenanthramides on Human Serum
Agricultural Sciences in China, 2011Abstract The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study. Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon. Plasma lipid peroxides and antioxidant status were measured.
Yang Yao, Gui-Xing Ren
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Tentative Avenanthramide‐Modifying Enzyme in Oats
Cereal Chemistry, 2003ABSTRACTA decrease of the concentration of the synthetic avenanthramide N‐(4′‐hydroxy‐(E)‐cinnamoyl)‐5‐hydroxyanthranilic acid in a buffered slurry of milled oat groats (Avena sativa L.) was temperature and pH‐dependent, with a maximum rate at 30°C and pH 9.
Susanne Bryngelsson +3 more
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Identification of a dehydrodimer of avenanthramide phytoalexin in oats
Tetrahedron, 2004A new compound (1) was found to accumulate when oat leaves were treated with elicitors. A reaction with peroxidase and avenanthramide B, an oat phytoalexin, in the presence of hydrogen peroxide resulted in the formation of 1. The chemical structure of 1 was determined to be a cyclic dehydrodimer of avenanthramide B based on spectroscopic analyses and ...
Yozo Okazaki +3 more
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Microbial‐derived metabolites of oat avenanthramides
The FASEB Journal, 2016Oat is a multifunctional crop nutritionally superior to many other unfortified cereals. It is commonly consumed as whole grains and known to provide healthy nutrients to humans. Oats contain a unique type of compounds, avenanthramides (AVAs), which are a group of substituted N ...
Aaron Yerke, Pei Wang, Shengmin Sang
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Avenanthramide-C prevents amyloid formation of bovine serum albumin
Biophysical Chemistry, 2020The misfolding of protein and its assembly into amyloid fibrils with a characteristic β-sheet-rich secondary structure, cause a lot of illnesses. Polyphenols have been extensively studied as a class of amyloid inhibitors, whose effect depends on the position and number of hydroxyl groups around the flavone backbone.
Maria Guadalupe, Quiroz Vazquez +3 more
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An alternative way to analogues of avenanthramides and their antiradical activity
Monatshefte für Chemie - Chemical Monthly, 2018The paper is devoted to the synthesis of arylidene malonic acid monoanilides and cinnamoyl anilines by condensation of malonic acid monoanilides with aromatic aldehydes. The presented synthetic route applies simple, cheap, and commercially available aromatic aldehydes and amines, thus overcoming traditional schemes, which involve derivatives of ...
Inese Mierina +3 more
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Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast
BioFactors, 2015AbstractSaccharomyces cerevisiae has been proven to be a valuable tool for the expression of plant metabolic pathways. By engineering a S. cerevisiae strain with two plant genes (4cl‐2 from tobacco and hct from globe artichoke) we previously set up a system for the production of two novel phenolic compounds, N‐(E)‐p‐coumaroyl‐3‐hydroxyanthranilic acid (
Moglia, A +10 more
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Chemotherapeutic Effects of Avenanthramides on Breast Cancer Cells
The FASEB Journal, 2017In the United States, nearly one in eight women will develop invasive breast cancer over the course of their life.
Jordan Hastings, Jason Kenealey
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The Pharmacology of Avenanthramides: Polyphenols
2018Ilias Marmouzi, Shahira M. Ezzat
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