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In Vitro Antioxidant Activity and Antigenotoxic Effects of Avenanthramides and Related Compounds
Journal of Agricultural and Food Chemistry, 2009 Avenanthramides are substituted N-cinnamoylanthranilic acids, with hydroxycinnamic acid and anthranilic acid moieties. These alkaloid phenols, which are unique to oats, may confer health benefits via antioxidant or other mechanisms. Synthetic avenanthramides, hydroxycinnamic acids, Tranilast, and ascorbic acid were evaluated for antioxidant activity ...
Ruth K Price +2 more
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Potential health benefits of avenanthramides of oats
Nutrition Reviews, 2009Oats are known to be a healthy food for the heart due mainly to their high beta-glucan content. In addition, they contain more than 20 unique polyphenols, avenanthramides, which have shown strong antioxidant activity in vitro and in vivo. The polyphenols of oats have also recently been shown to exhibit anti-inflammatory, antiproliferative, and anti ...
Mohsen Meydani, Meydani Mohsen
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Food Chemistry
Oat avenanthramides possess multiple biologically beneficial properties. However, their interaction with starch has not been investigated. This study aims to study the interactions between avenanthramides and starches using high-performance liquid chromatography, rapid viscosity analysis, and simulated digestion.
Chao Chen, Yijun Yao, Lifeng Wang
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Oat avenanthramides possess multiple biologically beneficial properties. However, their interaction with starch has not been investigated. This study aims to study the interactions between avenanthramides and starches using high-performance liquid chromatography, rapid viscosity analysis, and simulated digestion.
Chao Chen, Yijun Yao, Lifeng Wang
exaly +3 more sources
Yeast-Derived Recombinant Avenanthramides Inhibit Proliferation, Migration and Epithelial Mesenchymal Transition of Colon Cancer Cells [PDF]
Nutrients, 2018 Avenanthramides (Avns), polyphenols found exclusively in oats, are emerging as promising therapeutic candidates for the treatment of several human diseases, including colon cancer.
Federica Finetti +2 more
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Metabolism of avenanthramide phytoalexins in oats
The Plant Journal, 2004SummaryOat leaves produce phytoalexins, avenanthramides, in response to infection by pathogens or treatment with elicitors. The metabolism of avenanthramides was investigated using low molecular weight, partially deacetylated chitin as an elicitor. When oat leaf segments are floated on the elicitor solution, avenanthramides accumulate in the solution ...
Yozo, Okazaki +8 more
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Stability of Oat Avenanthramides
Cereal Chemistry, 2001ABSTRACTThe three main oat avenanthramides, N‐(4′‐hydroxy)‐(E)‐cinnamoyl‐5‐hydroxyanthranilic acid (Bp), N‐(4′‐hydroxy‐3′‐methoxy)‐(E)‐cinnamoyl‐5‐hydroxyanthranilic acid (Bf), and N‐(3′,4′‐dihydroxy)‐(E)‐cinnamoyl‐5‐hydroxyanthranilic acid (Bc), and their corresponding cinnamic acids, p‐coumaric (P), ferulic (F), and caffeic (C), were investigated for
Lena Häll Dimberg +3 more
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The inhibition of intestinal glucose absorption by oat‐derived avenanthramides
Journal of Food Biochemistry, 2022Avenanthramides are phenolic compounds unique to oats and may contribute to health-promoting properties associated with oat consumption. This study used Xenopus laevis oocytes expressing the glucose transporters, glucose transporter 2 (GLUT2) or sodium-glucose transport protein 1 (SGLT1) and human Caco-2 cells models to investigate the effect of oat ...
Haonan Zhouyao +5 more
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Biosynthesis of oat avenanthramide phytoalexins
Phytochemistry, 1999Abstract The biosynthesis of oat phytoalexins, avenanthramides, was investigated by administering labeled putative precursors to oat leaf segments treated with the elicitor, penta-N-acetylchitopentaose. Among the compounds tested, oat leaf segments incorporated [ring-UL-14C]anthranilic acid, [2,3,4,5,6-2H] l -phenylalanine and [1,2-13C]p-coumaric ...
Atsushi Ishihara +2 more
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Comprehensive Study of the Effect of Oat Grain Germination on the Content of Avenanthramides
Food Chemistry, 2023The chemical profile and the levels of AVNs in oat varieties after germination have been examinated. In the present study, 12 distinct oat varieties were germinated for 0-192 h and a total of 28 AVNs and 3 AVN-hexosides were determined in these samples. Among them, three novel AVNs were synthesized (AVN 1a, AVN 2a, and AVN 2ad), characterized using NMR
Michal Jágr +9 more
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New Dimeric Compounds of Avenanthramide Phytoalexin in Oats
The Journal of Organic Chemistry, 2007Avenanthramide B is an oat phytoalexin produced in response to pathogen attack and elicitation. We found the formation of new dimers (1-5) of avenanthramide B in elicited oat leaves. The dimers were synthesized by a reaction of peroxidase and avenanthramide B in the presence of hydrogen peroxide.
Yozo, Okazaki +4 more
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