Results 101 to 110 of about 4,712,566 (254)

Causal analysis of energy retrofit for real-life cases using Average Treatment Effect [PDF]

open access: yesE3S Web of Conferences
Energy retrofit of existing buildings is one of the key strategies for achieving building decarbonization. However, its actual impact on energy reduction remains underexplored due to unobserved confounding factors.
Lee Seung-Ju   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

MODE: Minimax Optimal Deterministic Experiments for Causal Inference in the Presence of Covariates

open access: yesEntropy
Data-driven decision-making has become crucial across various domains. Randomization and re-randomization are standard techniques employed in controlled experiments to estimate causal effects in the presence of numerous pre-treatment covariates.
Shaohua Xu, Songnan Liu, Yongdao Zhou
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Estimation of Heterogeneous Treatment Effects on Hazard Rates [PDF]

open access: yes
Consider a setting where a treatment that starts at some point during a spell (e.g. in unemployment) may impact on the hazard rate of the spell duration, and where the impact may be heterogeneous across subjects.
Gaure, Simen   +3 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Adaptive Experimental Design Using the Propensity Score [PDF]

open access: yes
Many social experiments are run in multiple waves, or are replications of earlier social experiments. In principle, the sampling design can be modified in later stages or replications to allow for more efficient estimation of causal effects.
Dean Karlan   +2 more
core   +3 more sources

Taking a New Look at Empirical Models of Adoption: Average Treatment Effect Estimation of Adoption Rates and their Determinants [PDF]

open access: yes
This paper shows that the observed sample adoption rate does not consistently estimate the population adoption rate even if the sample is random. It is proved that instead the sample adoption rate is a consistent estimate of the population joint exposure
Diagne, Aliou
core   +1 more source

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