Results 141 to 150 of about 4,704,446 (291)
A practical comparison of the bivariate probit and linear IV estimators [PDF]
This paper presents asymptotic theory and Monte-Carlo simulations comparing maximum-likelihood bivariate probit and linear instrumental variables estimators of treatment effects in models with a binary endogenous treatment and binary outcome.
Chiburis, Richard C. +2 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Impact of Measurement Error on Evaluation Methods Based on Strong Ignorability [PDF]
When selection bias can purely be attributed to observables, several estimators have been discussed in the literature to estimate the average effect of a binary treatment or policy on a scalar outcome.
Andrew Chesher, Erich Battistin
core
Estimation of the Local Conditional Tail Average Treatment Effect
Journal of Business & Economic StatisticsThe conditional tail average treatment effect (CTATE) is defined as a difference between the conditional tail expectations (CTE’s) of potential outcomes, which can capture heterogeneity and deliver aggregated local information on treatment effects over different quantile levels and is closely related to the notion of second-order stochastic dominance ...
Chen, Le-Yu, Yen, Yu-Min
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Local Instrumental Variables [PDF]
This paper unites the treatment effect literature and the latent variable literature. The economic questions answered by the commonly used treatment effect parameters are considered.
Edward J. Vytlacil, James J. Heckman
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
IDENTIFICATION AND INFERENCE FOR MARGINAL AVERAGE TREATMENT EFFECT ON THE TREATED WITH AN INSTRUMENTAL VARIABLE. [PDF]
Stat Sin, 2020 Liu L +4 more
europepmc +1 more source
Unbundling the Degree Effect in a Job Training Program for Disadvantaged Youth [PDF]
Government-sponsored education and training programs have the goal to enhance participants' skills so as to become more employable, productive and dependable citizens and thus alleviate poverty and decrease public dependence. While most of the literature
Bampasidou, Maria +2 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source