Results 51 to 60 of about 11,252,851 (310)

Averages of characteristic polynomials in random matrix theory [PDF]

Communications on Pure and Applied Mathematics, 2005
We compute averages of products and ratios of characteristic polynomials associated with Orthogonal, Unitary, and Symplectic Ensembles of Random Matrix Theory. The pfaffian/determinantal formulas for these averages are obtained, and the bulk scaling asymptotic limits are found for ensembles with Gaussian weights.
Borodin, A., Strahov, E.
openaire   +4 more sources

New Operators for Aggregating Intuitionistic Fuzzy Information With Their Application in Decision Making

IEEE Access, 2018
Aggregation of intuitionistic fuzzy information is a hot topic in Atanassov's intuitionistic fuzzy set theory, which has attracted much interest from researchers in recent years. In this paper, a series of new aggregation operators and weighted averaging
Cheng-Li Fan, Yafei Song, Qiang Fu, Lei Lei, Xiaodan Wang   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Average Predictability Time. Part I: Theory

Journal of the Atmospheric Sciences, 2009
AbstractThis paper introduces the average predictability time (APT) for characterizing the overall predictability of a system. APT is the integral of a predictability measure over all lead times. The underlying predictability measure is based on the Mahalanobis metric, which is invariant to linear transformation of the prediction variables and hence ...
Timothy DelSole, Michael K. Tippett
openaire   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Addendum to Higher order stroboscopic averaged functions: a general relationship with Melnikov functions

Electronic Journal of Qualitative Theory of Differential Equations
This addendum presents a relevant stronger consequence of the main theorem of the paper “Higher order stroboscopic averaged functions: a general relationship with Melnikov functions”, Electron. J. Qual. Theory Differ. Equ. 2021, No. 77.
Douglas Novaes
doaj   +1 more source

Periodic orbits near equilibria via averaging theory of second order

Mathematical Modelling and Analysis, 2012
Lyapunov, Weinstein and Moser obtained remarkable theorems giving sufficient conditions for the existence of periodic orbits emanating from an equilibrium point of a differential system with a first integral.
Luis Barreira, Jaume Llibre, Claudia Valls   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source