Results 61 to 70 of about 734,652 (287)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Refined algebraic quantisation with the triangular subgroup of SL(2,R)
, 2004 We investigate refined algebraic quantisation with group averaging in a constrained Hamiltonian system whose gauge group is the connected component of the lower triangular subgroup of SL(2,R). The unreduced phase space is T^*R^{p+q} with p>0 and q>0, and
ALBERTO MOLGADO +19 more
core +4 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Electronic Journal of Qualitative Theory of Differential EquationsThis addendum presents a relevant stronger consequence of the main theorem of the paper “Higher order stroboscopic averaged functions: a general relationship with Melnikov functions”, Electron. J. Qual. Theory Differ. Equ. 2021, No. 77.
Douglas Novaes
doaj +1 more source
Periodic orbits near equilibria via averaging theory of second order
Mathematical Modelling and Analysis, 2012 Lyapunov, Weinstein and Moser obtained remarkable theorems giving sufficient conditions for the existence of periodic orbits emanating from an equilibrium point of a differential system with a first integral.
Luis Barreira +2 more
doaj +1 more source
On quantum averaging, quantum KAM and quantum diffusion
, 2012 For nonautonomous Hamiltonian systems and their quantisations we discuss properties of the quantised systems, related to those of the corresponding classical systems, described by the KAM-related theories: the proper KAM, the averaging theory, the ...
A. I. Neishtadt +16 more
core +2 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Thermally-Assisted Spin-Transfer Torque Dynamics in Energy Space
, 2013 We consider the general Landau-Lifshitz-Gilbert theory underlying the magnetization dynamics of a macrospin magnet subject to spin-torque effects and thermal fluctuations.
Kent, Andrew D. +2 more
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Frontiers in Psychology, 2020 Empirical tests of Schwartz’s theory of culture-level value priorities have predominantly been performed using an averaging approach–as values of the average individual in a culture. However, from a theory of measurement standpoint such an approach seems
Erich H. Witte +4 more
doaj +1 more source