Results 51 to 60 of about 3,441 (241)

Chicken Glycogen Synthase Kinase 3β Suppresses Innate Immune Responses and Enhances Avian Leukosis Virus Replication in DF-1 Cells

Microbiology Spectrum, 2023
Glycogen synthase kinase 3β (GSK3β) is a widely distributed multifunctional serine/threonine kinase. In mammals, GSK3β regulates important life activities such as proinflammatory response, anti-inflammatory response, immunity, and cancer development ...
Zhouhao Cui, Bei Weng, Yongxiu Yao, Hongxia Shao, Jianqiang Ye, Aijian Qin, Kun Qian   +6 more
doaj   +1 more source

Immunological basis of differences in disease resistance in the chicken [PDF]

, 2002
Genetic resistance to diseases is a multigenic trait governed mainly by the immune system and its interactions with many physiologic and environmental factors.
Gruys, E., Huurne, A.A.H.M., ter, Landman, W.J.M., Pol, J.M.A., Rebel, J.M.J., Zekarias, B.   +5 more
core   +2 more sources

Genome-wide analysis reveals the extent of EAV-HP integration in domestic chicken [PDF]

, 2015
Background: EAV-HP is an ancient retrovirus pre-dating Gallus speciation, which continues to circulate in modern chicken populations, and led to the emergence of avian leukosis virus subgroup J causing significant economic losses to the poultry industry.
A Fumihito, A Kranis, A Matsukawa, Andrew S. Mason, AR Quinlan, C Butts, CH Chao, Chang-Yeon Cho, CN Ting, D Wragg, David W. Burt, David Wragg, DJ Lynn, DW Huang, E Paradis, F Moges, F Ronquist, F Supek, GO Sperber, H Li, H Li, H Sawai, H-J Megens, International Chicken Genome Sequencing Consortium, J Cook, J Denner, J Eriksson, J Reimand, J Reimand, J Sambrook, JC Deng, JD Thompson, JH Ward Jr, Joram M. Mwacharo, JP Stoye, K Grønskov, L Borisenko, L Villarreal, Le Yu, LM Smith, M Bolisetty, M Nethe, M Nishibori, MA Sacco, MA Sacco, MI Krzywinski, N Dana, Olivier Hanotte, P Jern, R Development Core Team, R Leinonen, Raman A. Lawal, Richard Kuo, RM Resnick, S Desfarges, S Kanginakudru, SC Burgess, Steve Kemp, T Kidd, Takele Taye Desta, TT Desta, W-L Fan, WK Ruan, Y-P Liu, Y-W Miao, Z Wang   +65 more
core   +6 more sources

gga-miR-375 plays a key role in tumorigenesis post subgroup J avian leukosis virus infection.

PLoS ONE, 2014
Avian leukosis is a neoplastic disease caused in part by subgroup J avian leukosis virus J (ALV-J). Micro ribonucleic acids (miRNAs) play pivotal oncogenic and tumour-suppressor roles in tumour development and progression.
Hongxin Li, Huiqing Shang, Dingming Shu, Huanmin Zhang, Jun Ji, Baoli Sun, Hongmei Li, Qingmei Xie   +7 more
doaj   +1 more source

A glance over the fence: Using phylogeny and species comparison for a better understanding of antigen recognition by human γδ T‐cells

Immunological Reviews, Volume 298, Issue 1, Page 218-236, November 2020., 2020
Abstract Both, jawless and jawed vertebrates possess three lymphocyte lineages defined by highly diverse antigen receptors: Two T‐cell‐ and one B‐cell‐like lineage. In both phylogenetic groups, the theoretically possible number of individual antigen receptor specificities can even outnumber that of lymphocytes of a whole organism.
Thomas Herrmann, Mohindar Murugesh Karunakaran, Alina Suzann Fichtner   +2 more
wiley   +1 more source

A metagenomic comparison of endemic viruses from broiler chickens with runting stunting syndrome and from normal birds [PDF]

, 2016
Runting-stunting syndrome (RSS) in broiler chickens is an enteric disease that causes significant economic losses to poultry producers worldwide due to elevated feed conversion ratios, decreased body weight during growth, and excessive culling.
Devaney, Ryan, Meharg, Caroline, Smyth, Victoria, Trudgett, Alan, Trudgett, James   +4 more
core   +1 more source

Evolutionary trajectory of fish Piscine novirhabdovirus (=Viral Hemorrhagic Septicemia Virus) across its Laurentian Great Lakes history: Spatial and temporal diversification

Ecology and Evolution, Volume 10, Issue 18, Page 9740-9775, September 2020., 2020
This study analyses the evolutionary trajectory of a novel virus over its 17‐year history, examining the dynamics of its host relationships and its patterns across geographic space and evolutionary time. We sequence its entire genome and discern that the virus has significantly changed, with its original genotypes disappearing and being replaced in a ...
Carol A. Stepien, Megan D. Niner
wiley   +1 more source

Seroprevalence of avian leukosis virus in local chickens in five live bird markets, Kaduna metropolis, North-western Nigeria [PDF]

, 2022
Avian leukosis virus is recognized as an important viral pathogen in the poultry industry, resulting in salient severe economic losses due to reduced production, uneven flock growth rates, reduced growth, and immunosuppression which predispose affected ...
Bakam, J.D., Bashir, M., Bitrus, I., Meseko, C.A., Shittu , I., Wungak, Y.S.   +5 more
core   +2 more sources

Modeling pediatric medulloblastoma

Brain Pathology, Volume 30, Issue 3, Page 703-712, May 2020., 2020
Abstract Mouse models of medulloblastoma have proven to be instrumental in understanding disease mechanisms, particularly the role of epigenetic and molecular drivers, and establishing appropriate preclinical pipelines. To date, our research community has developed murine models for all four groups of medulloblastoma, each of which will be critical for
Martine F. Roussel, Jennifer L. Stripay
wiley   +1 more source

Baicalin is an inhibitor of subgroup J avian leukosis virus infection

Virus Research, 2018
Avian leukosis virus subgroup J (ALV-J) can cause great economic losses to the poultry industry worldwide. Baicalin, one of the flavonoids present in S.baicalensis Georgi, has been shown to have antiviral activities. To investigate whether baicalin has antiviral effects on the infection of ALV-J in DF-1 cells, the cells were treated with baicalin at ...
Kun, Qian, Zheng-Ru, Kong, Jie, Zhang, Xiao-Wei, Cheng, Zong-Yi, Wu, Cheng-Xi, Gu, Hong-Xia, Shao, Ai-Jian, Qin   +7 more
openaire   +2 more sources