Results 81 to 90 of about 3,441 (241)

Extracellular RNA in viral–host interactions: Thinking outside the cell

WIREs RNA, Volume 10, Issue 4, July/August 2019., 2019
In normal physiology, host microRNAs (miRNAs) exported in extracellular vesicles (EVs) are involved in cell‐to‐cell communication and in maintaining homeostasis. Upon viral infection, the miRNA cargo of the EVs can be altered and enriched for specific (viral or host) miRNAs which influence immune responses in the recipient cell and alter the ...
Sarah Ressel, Adelina Rosca, Katrina Gordon, Amy H. Buck   +3 more
wiley   +1 more source

Rodent models of tumours of the central nervous system

Molecular Oncology, Volume 18, Issue 12, Page 2842-2870, December 2024.
We describe the evolution of experimental systems, illustrated here in a timeline to show changing popularity over time. Starting with chemical and viral carcinogenesis, systems then developed into increasingly sophisticated genetically modified animal models.
Sebastian Brandner
wiley   +1 more source

Detection of avian leukosis virus using polymerase chain reaction and enzyme linked immunosorbent assay [PDF]

, 2004
The applications of polymerase chain reaction (PCR) and enzyme linked immunosorbent assay (ELISA) in detecting avian leukosis virus (ALV) subgroups A and J were studied in a flock of breeder chickens. Out of 74 chickens tested 9, 36, 13 and 16 were found
Abd Rasid, Omar, Arshad, Siti Suri, Bejo, Mohd Hair, Md Mahfuzul Hoque,, Thapa Chhetri, Bala Ram   +4 more
core  

Identification and characterisation of endogenous Avian Leukosis Virus subgroup E (ALVE) insertions in chicken whole genome sequencing data [PDF]

, 2020
Background: Endogenous retroviruses (ERVs) are the remnants of retroviral infections which can elicit prolonged genomic and immunological stress on their host organism.
Burt, David W., Burt, David W., Fulton, Janet E., Hocking, Paul M., Lund, Ashlee R., Mason, Andrew S., Mason, Andrew S.   +6 more
core   +3 more sources

Molecular Detection and Genetic Characterization of Avian Leukosis Virus From Field Outbreaks in Bangladesh

Veterinary Medicine and Science, Volume 10, Issue 6, November 2024.
Histopathological examination of the liver from an avian leukosis virus (ALV)‐infected chicken reveals tissue alterations. Molecular detection confirms the presence of ALV in the liver samples. Evolutionary origin analysis traces the identified ALV strain. Mutational analysis and structural examination of the ALV envelope (Env) protein provide insights
Md. Golzar Hossain, Riman Pathan, SM Nazmul Hasan, Anandha Mozumder, Moslema Jahan Mou, Marjana Akter, Chandan Sikder, Riyan Al Islam Reshad, Roni Mia, Sukumar Saha, Tofazzal Islam, Sharmin Akter   +11 more
wiley   +1 more source

Oxidative Stress in Poultry: Lessons from the Viral Infections

Oxidative Medicine and Cellular Longevity, Volume 2018, Issue 1, 2018., 2018
Reactive species (RS), generally known as reactive oxygen species (ROS) and reactive nitrogen species (RNS), are produced during regular metabolism in the host and are required for many cellular processes such as cytokine transcription, immunomodulation, ion transport, and apoptosis.
Zaib Ur Rehman, Chunchun Meng, Yingjie Sun, Anum Safdar, Riaz Hussain Pasha, Muhammad Munir, Chan Ding, Angel Catalá   +7 more
wiley   +1 more source

Isolation, Molecular Characterisation, and Pathogenicity Analysis of a Novel Recombinant ALV‐J Strain Isolated From Chinese Hetian Chickens

Veterinary Medicine and Science, Volume 10, Issue 6, November 2024.
Reduced mortality: The isolated LY2021J strain of ALV‐J from Hetian chickens showed lower mortality despite causing severe dysplasia. Genetic similarity: LY2021J exhibited high genetic similarity to the Chinese Heilongjiang strain JS14NT01, particularly in the gp85 and pol genes, suggesting a possible common origin.
Tianyu Lei, Liyun Zhuang, Tingting Dai, Qun Niu, Yinli Bao, Weiming Lin, Cuiqin Huang, Xintian Zheng   +7 more
wiley   +1 more source

Antiviral Activity against Avian Leucosis Virus Subgroup J of Degraded Polysaccharides from Ulva pertusa

BioMed Research International, Volume 2018, Issue 1, 2018., 2018
Avian Leukosis Virus Subgroup J (ALV‐J), a retrovirus of avian, has caused enormous economics losses to poultry industry around the world. Polysaccharides from marine algae are featured diversity bioactivities. To find the potential effect to prevent ALV‐J spread, in this study, polysaccharides from Ulva pertusa (UPPs) and four low molecular weight (Mw)
Yuhao Sun, Xiaolin Chen, Lin Song, Song Liu, Huahua Yu, Xueqin Wang, Yukun Qin, Pengcheng Li, Heather Simpson   +8 more
wiley   +1 more source

Integrative RNA-seq and ChIP-seq analysis unveils metabolic regulation as a conserved antiviral mechanism of chicken p53

Microbiology Spectrum
The tumor suppressor p53, primarily functioning as a transcription factor, has exhibited antiviral capabilities against various viruses in chickens, including infectious bursal disease virus (IBDV), avian leukosis virus subgroup J (ALV-J), and avian ...
Lu Cui, Xuefeng Li, Zhijie Chen, Zheyi Liu, Yu Zhang, Zongxi Han, Shengwang Liu, Hai Li   +7 more
doaj   +1 more source

CH25H Promotes Autophagy and Regulates the Malignant Progression of Laryngeal Squamous Cell Carcinoma Through the PI3K‐AKT Pathway

Cancer Medicine, Volume 13, Issue 20, October 2024.
ABSTRACT Background Laryngeal squamous cell carcinoma (LSCC) is a type of cancer of the respiratory tract that often presents with subtle symptoms at the early stage and is susceptible to recurrence and metastasis. Materials and Methods To find out key regulatory genes involved in LSCC development, we downloaded LSCC‐related sequencing datasets for ...
Zhenfei Xiang, Senquan Yu, Yuxin Xu, Huacai Xiong, Danfei Hu, Qun Li, Zhenhua Wu   +6 more
wiley   +1 more source