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Temperature sensitive mutants of avian sarcoma viruses
Biochimica Et Biophysica Acta: Reviews on Cancer, 1975J Wyke
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Virus Research, 1988
Twelve independent isolates of avian sarcoma viruses (ASVs) can be divided into four groups according to the transforming genes harbored in the viral genomes. The first group is represented by viruses containing the transforming sequence, src, inserted in the viral genome as an independent gene; the other three groups of viruses contain transforming ...
L H, Wang, H, Hanafusa
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Twelve independent isolates of avian sarcoma viruses (ASVs) can be divided into four groups according to the transforming genes harbored in the viral genomes. The first group is represented by viruses containing the transforming sequence, src, inserted in the viral genome as an independent gene; the other three groups of viruses contain transforming ...
L H, Wang, H, Hanafusa
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Alterations in the genomes of avian sarcoma viruses
Virology, 1982We describe 12 nonconditional mutants of avian sarcoma virus. Eleven were replication defective and one appeared to retain wild-type functions. Comparison of restriction endonuclease digests of viral DNA revealed that 8 of 11 replication defectives contained large deletions of viral information.
Mason, W S +8 more
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Characteristics of cores of avian leuko-sarcoma viruses
Virology, 1970Abstract Rous sarcoma virus-Rous associated virus (RSV-RAV 1 ) mixtures were treated to remove lipoprotein envelopes, and the resulting virion cores were analyzed. Cores labeled with uridine- 3 H had a density (1.27 g/ml) different from intact virus (1.16 g/ml) and could be separated by isopycnic banding in potassium tartrate, cesium sulfate, or ...
J P, Bader, N R, Brown, A V, Bader
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Vectors derived from avian leukosis and sarcoma viruses
Journal of Molecular Medicine, 1995International ...
Flamant, Frederic +2 more
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Chemical crosslinking of proteins in avian sarcoma and leukemia viruses
Virology, 1980Abstract We have investigated the nearest neighbor relationships of proteins in avian sarcoma and leukemia viruses by means of bifunctional crosslinking agents. In intact virions dimethyl suberimidate and dithiobispropionimidate induce the formation of covalently linked multimeric species of all four internal structural proteins ( gag proteins).
R B, Pepinsky +3 more
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Avian sarcoma viruses, protein kinases and cell transformation
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1983Abstract The first RNA tumour virus to be isolated and identified as such was the Rous sarcoma virus (RSV), which causes the transformation of cells in culture as well as fibrosarcomas when injected into suitable host animals (for reviews see Hanafusa (1977) and Bishop (1978)).
R L, Erikson +3 more
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Polyethylene glycol-mediated infection with avian sarcoma viruses
Archives of Virology, 1978In this communication we report that fusion of viral and cellular membranes by polyethylene glycol is a convenient approach to overcoming genetically determined resistance to infection. Using this method, avian sarcoma virus-transformed mammalian cells have been produced which serve as useful model systems for the study of Rous sarcoma virus-specific ...
W, Rohde +3 more
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PRCII, a Representative of a New Class of Avian Sarcoma Viruses
1981The Poultry Research Center Virus II (PRC II) is a replication-defective avian sarcoma virus with envelope determinants of the A and B subgroups. In nonproducing cells transformed by PRCII the products of the replicative genes gag, pol, and env are not demonstrable, but a single polyprotein of Mr 105,000 (p105) can be detected.
P K, Vogt +3 more
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Defective Avian Sarcoma Viruses
1983This review was intended initially as a reference source for those interested in the origins and first descriptions of the defective avian sarcoma viruses. Quite a few of these viruses have been characterized in the past few years and their varied nomenclature according to source, discoverer, date of isolation or biological properties could result in ...
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