Results 31 to 40 of about 71,201 (184)

Binding of more than one Tva800 molecule is required for ASLV-A entry

Retrovirology, 2011
Background Understanding the mechanism by which viruses enter their target cell is an essential part of understanding their infectious cycle. Previous studies have focussed on the multiplicity of viral envelope proteins that need to bind to their cognate
Gray Eleanor R, Illingworth Christopher JR, Coffin John M, Stoye Jonathan P   +3 more
doaj   +1 more source

Membrane association of a 36,000-dalton substrate for tyrosine phosphorylation in chicken embryo fibroblasts transformed by avian sarcoma viruses

Journal of Cell Biology, 1983
A cellular protein of 36,000 daltons becomes phosphorylated at tyrosine in chicken embryo fibroblasts transformed with avian sarcoma viruses. We have used cellular fractionation and immunofluorescence to locate the 36-kdalton protein in virus-transformed
K. Radke, V. Carter, P. Moss, Philip Dehazya, Manfred Schliwa, G. Steven Martin   +5 more
semanticscholar   +1 more source

Berberine alleviates cell pyroptosis in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

Clinical Anatomy, Volume 39, Issue 3, Page 346-367, April 2026.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

Influenza virus infection drives upregulation of CD84 across a broad range of immune cells

Clinical &Translational Immunology, Volume 15, Issue 3, 2026.
Our findings reveal a link between high CD84 expression in humans and recovery from respiratory viral infections. In influenza virus‐infected mice, CD84 is upregulated on a broad range of innate and adaptive immune cell populations, particularly on activated and influenza virus‐specific T‐cell populations and associated with less disease severity ...
Xiaoxiao Jia, Isabelle JH Foo, Hayley A McQuilten, Jeremy Chase Crawford, Aira F Cabug, Deborah Gebregzabher, Janet Chou, Robert C Mettelman, Tanya Novak, Lee‐Ann Van de Velde, Ryan S Thwaites, Adrienne G Randolph, Paul G Thomas, Jianqing Xu, Zhongfang Wang, Katherine Kedzierska, Lukasz Kedzierski, Brendon Y Chua   +17 more
wiley   +1 more source

Plasma proteomic profiling and molecular clustering reveal immune‐defined prognostic subtypes in lung adenocarcinoma

International Journal of Cancer, Volume 158, Issue 4, Page 858-865, 15 February 2026.
What's new? Lung adenocarcinoma shows considerable heterogeneity in disease progression and therapeutic response. Here, the authors analyzed tumor samples through proteomic profiling and applied network‐based clustering. They identified two distinct patient groups with different demographic, clinical, and molecular characteristics.
Ujjwal Neogi, Anoop T. Ambikan, Kati Turkowski, Marc A. Schneider, Vanessa M. Beutgen, Johannes Graumann, Hauke Winter, Marek Bartkuhn, Werner Seeger, Soni S. Pullamsetti, Rajkumar Savai   +10 more
wiley   +1 more source

Assessing the validity of leucine zipper constructs predicted by AlphaFold

Protein Science, Volume 35, Issue 1, January 2026.
Abstract AP‐1 transcription factors are a network of cellular regulators that combine in different dimer pairs to control a range of pathways involved in differentiation, growth, and cell death. They dimerize via leucine zipper coiled‐coil domains that are preceded by a basic DNA binding domain.
Isobel Mitic, Keiran Rowell, Thomas Litfin, Katharine A. Michie, David A. Jacques   +4 more
wiley   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, Volume 12, Issue 48, December 29, 2025.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source

Brain‐Wide Connectivity Patterns of Feedforward and Feedback Cortico‐Cortical Neurons in the Mouse Secondary Visual Cortex

Journal of Comparative Neurology, Volume 533, Issue 12, December 2025.
Using projection‐ and layer‐specific rabies tracing, we mapped brain‐wide inputs to multiple feedforward and feedback neuron types in VISl (LM), the mouse secondary visual cortex. Although input patterns were broadly similar across neuron types, we observed differences in the relative contributions of visual, retrosplenial, and auditory cortices ...
Richard G. Dickson, Matthew W. Jacobs, John M. Ratliff, Alec L. R. Soronow, Faye An, Walid A. Yuqob, Euiseok J. Kim   +6 more
wiley   +1 more source