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Avibactam Pharmacokinetic/Pharmacodynamic Targets [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2018
Avibactam is a novel non--lactam -lactamase inhibitor that has been approved in the United States and Europe for use in combination with ceftazidime.
Shampa Das   +2 more
exaly   +2 more sources

In vivo emergence of cefiderocol and ceftazidime/avibactam cross-resistance in KPC-producing Klebsiella pneumoniae following ceftazidime/avibactam -based therapies [PDF]

open access: yesDiagnostic Microbiology and Infectious Disease
We described the emergence of ceftazidime/avibactam and cefiderocol cross-resistance in patients with KPC-producing Klebsiella pneumoniae infections. All strains with ceftazidime/avibactam and cefiderocol cross-resistance showed point mutations on KPC Ω ...
Maddalena Giannella   +2 more
exaly   +3 more sources

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