Results 21 to 30 of about 90,586 (267)

Facile synthesis of 1H-imidazo[1,2-b]pyrazoles via a sequential one-pot synthetic approach

Beilstein Journal of Organic Chemistry, 2014
5-Aminopyrazole-4-carbonitrile and ethyl 5-aminopyrazole-4-carboxylate, as potential trifunctional building blocks are introduced in a facile, chemo- and regioselective multicomponent assembly of imidazo[1,2-b]pyrazoles via the Groebke–Blackburn–Bienaymé
András Demjén, Márió Gyuris, János Wölfling, László G. Puskás, Iván Kanizsai   +4 more
doaj   +1 more source

The hidden function of egg white antimicrobials: egg weight-dependent effects of avidin on avian embryo survival and hatchling phenotype

Biology Open, 2018
Avidin is a key egg white antimicrobial protein with strong binding capacity for biotin, an essential growth and immune cell precursor. As such, it is assumed to have a pronounced, though still poorly explored, effect on hatchling phenotype.
Eva Krkavcová, Jakub Kreisinger, Ludmila Hyánková, Pavel Hyršl, Veronika Javůrková   +4 more
doaj   +1 more source

pH-Dependent Deformations of the Energy Landscape of Avidin-like Proteins Investigated by Single Molecule Force Spectroscopy

Molecules, 2014
Avidin and avidin-like proteins are widely used in numerous techniques since the avidin-biotin interaction is known to be very robust and reliable. Within this study, we investigated this bond at the molecular level under harsh conditions ranging from ...
Melanie Köhler, Andreas Karner, Michael Leitner, Vesa P. Hytönen, Markku Kulomaa, Peter Hinterdorfer, Andreas Ebner   +6 more
doaj   +1 more source

Biotin-Avidin-Mediated Capture of Microspheres on Polymer Fibers

Molecules, 2019
Systems for efficient and selective capture of micro-scale objects and structures have application in many areas and are of particular relevance for selective isolation of mammalian cells. Systems for the latter should also not interfere with the biology
Lucas Ahrens, Daniel Vonwil, Neha Arya, Aurelien Forget, V. Prasad Shastri   +4 more
doaj   +1 more source

Maximized nanodrug-loaded mesenchymal stem cells by a dual drug-loaded mode for the systemic treatment of metastatic lung cancer

Drug Delivery, 2017
Mesenchymal stem cells (MSCs), exhibiting tumor-tropic and migratory potential, can serve as cellular carriers to improve the effectiveness of anticancer agents.
Sen Yao, Xuqian Li, Jingxuan Liu, Yuqing Sun, Zhuanhe Wang, Yanyan Jiang   +5 more
doaj   +1 more source

Binding Properties of HABA-Type Azo Derivatives to Avidin and Avidin-Related Protein 4 [PDF]

, 2006
SummaryThe chicken genome encodes several biotin-binding proteins, including avidin and avidin-related protein 4 (AVR4). In addition to D-biotin, avidin binds an azo dye compound, 4-hydroxyazobenzene-2-carboxylic acid (HABA), but the HABA-binding ...
Repo, Susanna, Slotte, J. Peter, Paldanius, Tiina A., Halling, Katrin K., Rissanen, Kari, Johnson, Mark S., Pentikäinen, Olli T., Salminen, Tiina A., Huuskonen, Juhani, Hytönen, Vesa P., Airenne, Tomi T., Kulomaa, Markku S., Nyholm, Thomas K.M.   +12 more
core   +1 more source

Electrochemical sensing of biotin-avidin interaction on gold electrode modified by silver nanoparticles through covalent co-assembling

Sensors International, 2022
Electrochemical sensing of biotin-avidin interaction was investigated on gold electrode modified with 3-mercaptopropanoic acid (MPA) successively co-assembled with cysteamine functionalized silver nanoparticles and biotin or avidin.
Nirgaman Bage, Pradip Kar
doaj   +1 more source

Three-dimensional structures of avidin and the avidin-biotin complex. [PDF]

Proceedings of the National Academy of Sciences, 1993
The crystal structures of a deglycosylated form of the egg-white glycoprotein avidin and of its complex with biotin have been determined to 2.6 and 3.0 A, respectively. The structures reveal the amino acid residues critical for stabilization of the tetrameric assembly and for the exceptionally tight binding of biotin.
O, Livnah, E A, Bayer, M, Wilchek, J L, Sussman   +3 more
openaire   +2 more sources

The use of non-radioactive iodine as a label in immunoassays [PDF]

, 1995
The research described in this thesis has centered on the development of a nonradioactive iodine label for use in immunoassays. A protein can be iodinated with nonradioactive iodine, used in an immunoassay, and the iodine label detected by a chemical ...
Butler, Mary
core   +2 more sources

Thiol- and Biotin-Labeled Probes for Oligonucleotide Quartz Crystal Microbalance Biosensors of Microalga Alexandrium Minutum

Biosensors, 2012
Two quartz crystal microbalance oligonucleotide biosensors of a toxic microalga gene sequence (Alexandrium Minutum) have been designed. Grafting on a gold surface of 20-base thiol- or biotin-labeled probe, and selective hybridization with the ...
Mathieu Lazerges, Hubert Perrot, Niriniony Rabehagasoa, Chantal Compère   +3 more
doaj   +1 more source