Results 11 to 20 of about 90,586 (267)

Synthesis and Cytoprotective Characterization of 8-Hydroxyquinoline Betti Products

open access: yesMolecules, 2018
The 8-hydroxyquinoline pharmacophore scaffold has been shown to possess a range of activities as metal chelation, enzyme inhibition, cytotoxicity, and cytoprotection.
Iván Kanizsai   +6 more
doaj   +1 more source

Synthesis of N-peptide-6-amino-D-luciferin Conjugates

open access: yesFrontiers in Chemistry, 2018
A general strategy for the synthesis of N-peptide-6-amino-D-luciferin conjugates has been developed. The applicability of the strategy was demonstrated with the preparation of a known substrate, N-Z-Asp-Glu-Val-Asp-6-amino-D-luciferin (N-Z-DEVD-aLuc).
Anita K. Kovács   +8 more
doaj   +1 more source

Biotinylated Quinone as a Chemiluminescence Sensor for Biotin-Avidin Interaction and Biotin Detection Application

open access: yesSensors, 2023
Biotin, or vitamin B7, is essential for metabolic reactions. It must be obtained from external sources such as food and biotin/vitamin supplements because it is not biosynthesized by mammals.
Fatema Kaladari   +4 more
doaj   +1 more source

The chicken avidin gene family : organization, evolution and frequent recombination

open access: yes, 2021
Avidin is a biotin-binding protein found in chicken eggs. The gene encoding avidin (AVD) belongs to a family of multiple homologous genes, five of which (avidin-related genes 1-5 or AVRs 1-5) were previously cloned and sequenced.
Ahlroth, Mervi
core   +1 more source

Purification and crystallization of avidin [PDF]

open access: yesBiochemical Journal, 1970
An improved purification, including crystallization, of avidin from hen's-egg white is described. The product bound 15.1μg of biotin/mg, corresponding to an equivalent weight of 16200. The amino acid composition showed an integral number of amino acid residues per 16200g, which suggested that each molecule of avidin (mol. wt. approx.
N M, Green, E J, Toms
openaire   +2 more sources

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

open access: yesHepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo   +14 more
wiley   +1 more source

Effects of Biotin-Avidin Interactions on Hydrogel Swelling

open access: yesFrontiers in Chemistry, 2020
Affinity interactions between the small molecule biotin and the protein avidin have been used extensively to functionalize biomaterials. More recently, researchers have leveraged the changes in biotin-avidin affinity that occur upon biotin conjugation to
Talaial B. Alina   +3 more
doaj   +1 more source

A Systematic Study and Potential Limitations of Proton-ELISA Platform for α-Synuclein Antigen Detection

open access: yesChemosensors, 2021
To evaluate point-of-care testing (POCT) for the potential early detection of biomarkers of Parkinson’s disease, a systematic investigation of portable and low-cost platforms is performed based on the Proton-enzyme-linked immunosorbent assay (Proton ...
Chia-Ming Yang   +3 more
doaj   +1 more source

Structural Characterization of the Avidin Interactions with Fluorescent Pyrene-Conjugates: 1-Biotinylpyrene and 1-Desthiobiotinylpyrene

open access: yesMolecules, 2016
Avidin is a tetrameric protein that belongs to the calycin superfamily. It has been studied mainly because of its extraordinary affinity to biotin, which led to a wide range of applications based on the avidin-biotin system.
Paweł Strzelczyk   +3 more
doaj   +1 more source

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