Results 41 to 50 of about 694,679 (300)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Advances in myopia research anatomical findings in highly myopic eyes

Eye and Vision, 2020
Background The goal of this review is to summarize structural and anatomical changes associated with high myopia. Main text Axial elongation in myopic eyes is associated with retinal thinning and a reduced density of retinal pigment epithelium (RPE ...
Jost B. Jonas, Ya Xing Wang, Li Dong, Yin Guo, Songhomitra Panda-Jonas   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Evaluation of different techniques of measurement of the axial length in silicone oil-filled eyes

Journal of the Egyptian Ophthalmological Society
Purpose To evaluate different techniques of axial length measurement in silicone oil-filled eyes and compare the results of each with the original axial length measured before pars plana vitrectomy and silicone oil injection for accurate measurement of ...
Ghada A. Nassar, Ehsan El-Mehelmy, Kirollos Joseph, Ahmed A. Mohalhal   +3 more
doaj   +1 more source

Axial length in unilateral idiopathic central serous chorioretinopathy [PDF]

International Journal of Ophthalmology, 2016
AIM: To evaluate the axial length (AXL) in unilateral idiopathic central serous chorioretinopathy (CSC). METHODS: This retrospective case-control study was comprised of a consecutive case series of 35 patients with acute unilateral idiopathic CSC, and ...
Hoseok Moon, Dae Yeong Lee, Dong Heun Nam   +2 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Axial Length Correction in Evaluation of Refractive Predictability and Biometry Agreement [Letter]

Clinical Ophthalmology, 2023
Ferdinando Cione, Gerardo La Padula, Antonio Formicola Eye Unit, Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Salerno, ItalyCorrespondence: Gerardo La Padula, Eye Unit, Department of Medicine, Surgery ...
Cione F, La Padula G, Formicola A
doaj  

Modelling the Galactic bar using OGLE-II Red Clump Giant Stars [PDF]

, 2007
Red clump giant stars can be used as distance indicators to trace the mass distribution of the Galactic bar. We use RCG stars from 44 bulge fields from the OGLE-II microlensing collaboration database to constrain analytic tri-axial models for the ...
Mao, Shude, Rattenbury, Nicholas J., Smith, Martin C., Sumi, Takahiro   +3 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Capillary Condensation in Cylindrical Pores: Monte Carlo Study of the Interplay of Surface and Finite Size Effects

, 2010
When a fluid that undergoes a vapor to liquid transition in the bulk is confined to a long cylindrical pore, the phase transition is shifted (mostly due to surface effects at the walls of the pore) and rounded (due to finite size effects).
Binder, Kurt, Virnau, Peter, Wilms, Dorothea, Winkler, Alexander   +3 more
core   +1 more source