Results 151 to 160 of about 117,469 (259)

Molecular Dissection of DAAM Function during Axon Growth in Drosophila Embryonic Neurons. [PDF]

Cells, 2022
Földi I, Tóth K, Gombos R, Gaszler P, Görög P, Zygouras I, Bugyi B, Mihály J.   +7 more
europepmc   +1 more source

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

Engineered Neural Tissue (EngNT) Containing Human iPSC-Derived Schwann Cell Precursors Promotes Axon Growth in a Rat Model of Peripheral Nerve Injury. [PDF]

Bioengineering (Basel)
Powell RA, Atkinson EA, Smith PO, Patani R, Jat PS, Guillemot-Legris O, Phillips JB.   +6 more
europepmc   +1 more source

Sema6D Regulates Zebrafish Vascular Patterning and Motor Neuronal Axon Growth in Spinal Cord. [PDF]

Front Mol Neurosci, 2022
Sheng J, Xu J, Geng K, Liu D.
europepmc   +1 more source

Modelling Axonal Growth

, 2016
O crescimento axonal é um processo biológico importante e complexo, essencial para a fisiologia humana. Descobertas recentes demonstraram que a tradução de mRNA em neurónios ocorre não só no corpo celular como também no cone de crescimento, a estrutura responsável pela orientação axonal e seu consequente crescimento.
openaire   +1 more source

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

Advanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando, Emanuele Buratti, Francesca Paron   +2 more
wiley   +1 more source

Ptbp2 re-expression rescues axon growth defects in Smn-deficient motoneurons. [PDF]

Front Mol Neurosci
Salehi S, Zare A, Gandhi G, Sendtner M, Briese M.   +4 more
europepmc   +1 more source

Tension as a regulator and integrator of axonal growth [PDF]

Cell Motility, 1990
S R, Heidemann, R E, Buxbaum
openaire   +2 more sources

HLA‐DR+ Schwann Cells Generate the Protumor Cancer‐Neuron‐Immune Niche in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
Hijacked and educated by HNSCC cells, HLA‐DR+ Schwann cells lost their normal neural‐related functions but acquired immunoregulatory phenotypes to promote CD4+ T cells transform into Tregs. HLA‐DR+ Schwann cells induced a macrophage subpopulation, Il1β.
Xiaoyan Meng, Zhonglong Liu, Shijian Zhang, Luoman Gan, Liren Cao, Jingjing Sun, Lingfang Zhang, Yue He   +7 more
wiley   +1 more source

Molecular signaling predicts corticospinal axon growth state and muscle response plasticity induced by neuromodulation. [PDF]

Proc Natl Acad Sci U S A
Zareen N, Yung H, Kaczetow W, Glattstein A, Mazalkova E, Alexander H, Chen L, Parra LC, Martin JH.   +8 more
europepmc   +1 more source