Downregulation of EphB2 by RNA interference attenuates glial/fibrotic scar formation and promotes axon growth. [PDF]
Wu J +5 more
europepmc +1 more source
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
The Impact of Treadmill Training on Tissue Integrity, Axon Growth, and Astrocyte Modulation. [PDF]
Ageeva T +10 more
europepmc +1 more source
Parametric Analysis of Spiking Neurons in 16 nm Fin Field‐Effect Transistor Technology
Energy efficient computing has driven a shift toward brain‐inspired neuromorphic hardware. This study explores the design of three distinct silicon neuron topologies implemented in 16 nm fin field‐Effect transistor technology. While the Axon‐Hillock design achieves gigahertz throughput, its functional fragility persists. The Morris–Lecar model captures
Logan Larsh +3 more
wiley +1 more source
Stiffness-tunable biomaterials provide a good extracellular matrix environment for axon growth and regeneration. [PDF]
Han R +6 more
europepmc +1 more source
Thermally Stable Organic Synaptic Transistors Using a High‐Tg Polymer Electret
A high–glass‐transition‐temperature cyclic olefin copolymer (COC) electret enables thermally stable organic synaptic transistors for neuromorphic operation in harsh environments. UV–ozone treatment increases the trap density in COC, providing robust multilevel conductance and key synaptic functions (excitatory postsynaptic current/ inhibitory ...
Hoyoung Cho +9 more
wiley +1 more source
Strain-induced bands of Büngner formation promotes axon growth in 3D tissue-engineered constructs. [PDF]
Hromada C +6 more
europepmc +1 more source
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao +5 more
wiley +1 more source
Multiple guidance mechanisms control axon growth to generate precise T-shaped bifurcation during dorsal funiculus development in the spinal cord. [PDF]
Curran BM +6 more
europepmc +1 more source
Research progress on biomarkers of traumatic brain injury
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen +8 more
wiley +1 more source

