Results 221 to 230 of about 117,469 (259)

Growth and degeneration of axons on astrocyte surfaces: Effects on extracellular matrix and on later axonal growth

Glia, 1993
AbstractCultured astrocytes deposit an extracellular matrix which has been shown by immunocytochemistry to react with antibodies to tenascin, laminin, and fibronectin. Neuronal‐glial interaction down‐regulates these components of the matrix, causing a reduction in extracellular matrix localized to areas of contact with axons.
M D, Ard, M, Schachner, J T, Rapp, A, Faissner   +3 more
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Oligodendrocytes repel axons and cause axonal growth cone collapse

Journal of Cell Science, 1989
ABSTRACT We have examined the interactions between axons regenerating from dorsal root ganglia (DRGs) derived from newborn rats and oligodendrocytes cultured by three different techniques. Cultures examined after 2 days have a profuse outgrowth of axons from the DRGs, forming a dense mat on the culture surface.
J W, Fawcett, J, Rokos, I, Bakst
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Axonal growth and guidance

Trends in Neurosciences, 1983
Abstract The motile behavior of growing nerve tips expands the front margins of the neurite and generates mechanical forces that pull neurite components forwards. These activities promote the assembly and organization of cell components into the growing nerve fiber.
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Inhibition of axonal growth by a monoclonal antibody

Nature, 1983
Little is known about factors which control the outgrowth of neurites in the central nervous system (CNS) during development, although in vitro studies with neurones from the peripheral nervous system have shown that neurites require an appropriate substrate and specific factors for growth.
S, Henke-Fahle, F, Bonhoeffer
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Growth and elongation within and along the axon

Developmental Neurobiology, 2009
AbstractMechanical tension is a particularly effective stimulus for axonal elongation, but little is known about how it leads to the formation of new axon. To better understand this process, we examined the movement of axonal branch points, beads bound to the axon, and docked mitochondria while monitoring axonal width. We found these markers moved in a
Phillip, Lamoureux, Steven R, Heidemann, Nathan R, Martzke, Kyle E, Miller   +3 more
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The Role of Serotonin in Axon and Dendrite Growth

2012
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) plays multiple roles in the enteric, peripheral, and central nervous systems (CNS). Although its most prominent biological function is as a signal transmission messenger from pre- to postsynaptic neurons, other roles such as shaping brain development and regulating neurite growth have also been
Ephraim F, Trakhtenberg, Jeffrey L, Goldberg   +1 more
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Axon Growth and Guidance

2007
CONTENT Contents xiii PREFACE ... vii 1. MOLECULAR MECHANISMS OF AXONAL GROWTH ... 1 Celine Bouquet and Fatiha Nothias Introduction ...1 The Neuronal Growth Cone and its Cytoskeletal Organization ... 1 Mechanisms of Axonal Elongation ... 6 Regulation of the Cytoskeleton by Extracellular Cues, Role of Rho-GTPases ... 7 Growth Cone of Regenerating Axons .
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Axon Guidance: Growth cones say no

Current Biology, 1994
A recently characterized protein stops developing axons from growing; a gene family encoding related molecules has also been described.
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Cellular mechanisms in axonal growth

Experimental Neurology, 1979
R P, Veraa, B, Grafstein, R A, Ross
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Regulation of Axonal Growth

1988
A major manifestation of neural plasticity is the ability of adult nerve cells to regulate the growth of their axons. For example, peripheral nerve injury can be followed by the regeneration of the severed axons and the sprouting of intact axons. These two modes of growth may result in new synapse formation and therefore bear functional significance ...
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