Results 331 to 340 of about 6,133,766 (357)
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Neurotrophic factors and axonal growth
Current Opinion in Neurobiology, 2002Neuronal morphological differentiation is regulated by numerous polypeptide growth factors (neurotrophic factors). Recently, significant progress has been achieved in clarifying the roles of neurotrophins as well as glial cell line-derived neurotrophic factor family members in peripheral axon elongation during development.
Annette Markus +2 more
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Axonal Growth-Associated Proteins
Annual Review of Neuroscience, 1989Elongation ofaxons and active remodeling of their terminal arbors under lies the assembly of neural circuits during development, determines the success or fai lure of nerve regeneration, and may contribute to some forms of synaptic plast icity in adult brains.
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Glia, 1993
AbstractCultured astrocytes deposit an extracellular matrix which has been shown by immunocytochemistry to react with antibodies to tenascin, laminin, and fibronectin. Neuronal‐glial interaction down‐regulates these components of the matrix, causing a reduction in extracellular matrix localized to areas of contact with axons.
March D. Ard +3 more
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AbstractCultured astrocytes deposit an extracellular matrix which has been shown by immunocytochemistry to react with antibodies to tenascin, laminin, and fibronectin. Neuronal‐glial interaction down‐regulates these components of the matrix, causing a reduction in extracellular matrix localized to areas of contact with axons.
March D. Ard +3 more
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Oligodendrocytes repel axons and cause axonal growth cone collapse
Journal of Cell Science, 1989ABSTRACT We have examined the interactions between axons regenerating from dorsal root ganglia (DRGs) derived from newborn rats and oligodendrocytes cultured by three different techniques. Cultures examined after 2 days have a profuse outgrowth of axons from the DRGs, forming a dense mat on the culture surface.
J Rokos, James W. Fawcett, I Bakst
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Inhibition of axonal growth by a monoclonal antibody
Nature, 1983Little is known about factors which control the outgrowth of neurites in the central nervous system (CNS) during development, although in vitro studies with neurones from the peripheral nervous system have shown that neurites require an appropriate substrate and specific factors for growth.
Friedrich Bonhoeffer, Sigrid Henke-Fahle
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Nuclear Power for Axonal Growth
Science, 2009A transcription factor involved in oncogenesis and stem cell biology also controls neuronal axon outgrowth.
M. C. Subang, P. M. Richardson
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Growth and elongation within and along the axon
Developmental Neurobiology, 2009AbstractMechanical tension is a particularly effective stimulus for axonal elongation, but little is known about how it leads to the formation of new axon. To better understand this process, we examined the movement of axonal branch points, beads bound to the axon, and docked mitochondria while monitoring axonal width. We found these markers moved in a
Steven R. Heidemann +3 more
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2007
CONTENT Contents xiii PREFACE ... vii 1. MOLECULAR MECHANISMS OF AXONAL GROWTH ... 1 Celine Bouquet and Fatiha Nothias Introduction ...1 The Neuronal Growth Cone and its Cytoskeletal Organization ... 1 Mechanisms of Axonal Elongation ... 6 Regulation of the Cytoskeleton by Extracellular Cues, Role of Rho-GTPases ... 7 Growth Cone of Regenerating Axons .
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CONTENT Contents xiii PREFACE ... vii 1. MOLECULAR MECHANISMS OF AXONAL GROWTH ... 1 Celine Bouquet and Fatiha Nothias Introduction ...1 The Neuronal Growth Cone and its Cytoskeletal Organization ... 1 Mechanisms of Axonal Elongation ... 6 Regulation of the Cytoskeleton by Extracellular Cues, Role of Rho-GTPases ... 7 Growth Cone of Regenerating Axons .
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1988
A major manifestation of neural plasticity is the ability of adult nerve cells to regulate the growth of their axons. For example, peripheral nerve injury can be followed by the regeneration of the severed axons and the sprouting of intact axons. These two modes of growth may result in new synapse formation and therefore bear functional significance ...
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A major manifestation of neural plasticity is the ability of adult nerve cells to regulate the growth of their axons. For example, peripheral nerve injury can be followed by the regeneration of the severed axons and the sprouting of intact axons. These two modes of growth may result in new synapse formation and therefore bear functional significance ...
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The Role of Axonal Transport in the Growth of the Olfactory Nerve Axons
1982Numerous studies have analyzed changes in axonal transport that accompany nerve regeneration. These investigations have generally been carried out in vertebrate peripheral nerve or in lower vertebrate optic nerve, systems in which nerve injury is followed by rapid distal degeneration and regrowth of injured axons.
John S. Elam, P. Cancalon, G. J. Cole
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