Results 101 to 110 of about 102,974 (302)
Mathematical guidance for axons
Trends in Neurosciences, 1998 Axon guidance by gradients plays an important role in wiring up the developing nervous system. Growth cones seem to sense a concentration difference across their spatial extent, and convert this into a signal to move up or down a gradient. In this article, a simple mathematical framework is developed to understand when and where gradient detection can ...
openaire +3 more sources
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Advanced Healthcare Materials, EarlyView.Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami +4 more
wiley +1 more source
Axon and dendrite geography predict the specificity of synaptic connections in a functioning spinal cord network [PDF]
, 2007 Background: How specific are the synaptic connections formed as neuronal networks develop and can simple rules account for the formation of functioning circuits?
Borisyuk, Roman +5 more
core +4 more sources
Axon Guidance: FLRTing Promotes Attraction [PDF]
Current Biology, 2014 A recent study demonstrates a new mechanism by which crosstalk between multiple guidance cues is integrated during axon pathfinding. FLRT3 is a novel co-receptor for Robo1 that acts as a context-dependent modulator of Netrin-1 attraction in thalamocortical axons.
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji +7 more
wiley +1 more source
miR-92 Suppresses Robo1 Translation to Modulate Slit Sensitivity in Commissural Axon Guidance
Cell Reports, 2018 Summary: Temporospatial regulation of guidance signaling is essential for axon outgrowth and pathfinding in the developing nervous system. Regulation of Robo1 levels in commissural neurons modulates Slit sensitivity facilitating proper axon guidance. The
Tao Yang +5 more
doaj +1 more source
DIP2B Interacts With α-Tubulin to Regulate Axon Outgrowth
Frontiers in Cellular Neuroscience, 2020 Axonal development is essential to the establishment of neuronal morphology and circuitry, although the mechanisms underlying axonal outgrowth during the early developmental stages remain unclear.
Zhen-Kai Xing +8 more
doaj +1 more source
VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain [PDF]
, 2015 © 2015. Published by The Company of Biologists Ltd. This research was funded by a Wellcome Trust PhD fellowship to M.T. [092839/Z/10/Z] and a BBSRC project grant to C.R. and L.E. [BB/J00930X/1].
Cariboni, Anna +6 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi +2 more
wiley +1 more source
Revisiting Netrin-1: One Who Guides (Axons)
Frontiers in Cellular Neuroscience, 2018 Proper patterning of the nervous system requires that developing axons find appropriate postsynaptic partners; this entails microns to meters of extension through an extracellular milieu exhibiting a wide range of mechanical and chemical properties. Thus,
Nicholas P. Boyer +2 more
doaj +1 more source