Results 101 to 110 of about 104,244 (349)
Advanced Functional Materials, EarlyView.A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta +4 more
wiley +1 more source
A multi-protein receptor-ligand complex underlies combinatorial dendrite guidance choices in C. elegans. [PDF]
, 2016 Ligand receptor interactions instruct axon guidance during development. How dendrites are guided to specific targets is less understood. The C. elegans PVD sensory neuron innervates muscle-skin interface with its elaborate dendritic branches.
Dong, Xintong +5 more
core +2 more sources
Motor axon guidance in Drosophila
Seminars in Cell & Developmental Biology, 2019 The Drosophila motor system starts to assemble during embryonic development. It is composed of 30 muscles per abdominal hemisegment and 36 motor neurons assembling into nerve branches to exit the CNS, navigate within the muscle field and finally establish specific connections with their target muscles. Several families of guidance molecules that play a
Aref, Arzan Zarin, Juan-Pablo, Labrador
openaire +4 more sources
Advanced Healthcare Materials, EarlyView.A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li +8 more
wiley +1 more source
, 2004 The mammalian cortex is divided into architectonic and functionally distinct areas. There is growing experimental evidence that their emergence and development is controlled by both epigenetic and genetic factors.
Ermentrout, G. B., Karbowski, Jan
core +3 more sources
Translating Axon Guidance Cues [PDF]
Cell, 2002 Recent studies suggest that local translation of mRNA within axons plays a key role in two aspects of growth cone navigation. One line of evidence implies a local synthesis of proteins that mediate growth cone collapse and turning in response to guidance cues; another indicates that growth cones possess the machinery that would allow the local ...
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
miR-92 Suppresses Robo1 Translation to Modulate Slit Sensitivity in Commissural Axon Guidance
Cell Reports, 2018 Summary: Temporospatial regulation of guidance signaling is essential for axon outgrowth and pathfinding in the developing nervous system. Regulation of Robo1 levels in commissural neurons modulates Slit sensitivity facilitating proper axon guidance. The
Tao Yang +5 more
doaj +1 more source
Tyrosine kinase inhibition produces specific alterations in axon guidance in the grasshopper embryo [PDF]
, 1998 Tyrosine kinase signaling pathways are essential for process outgrowth and guidance during nervous system development. We have examined the roles of tyrosine kinase activity in programming growth cone guidance decisions in an intact nervous system in ...
Menon, Kaushiki P., Zinn, Kai
core
PlexinA3 restricts spinal exit points and branching of trunk motor nerves in embryonic zebrafish [PDF]
, 2007 The pioneering primary motor axons in the zebrafish trunk are guided by multiple cues along their pathways. Plexins are receptor components for semaphorins that influence motor axon growth and path finding.
Becker, Catherina G. +6 more
core +3 more sources