Results 121 to 130 of about 105,575 (349)
Signaling mechanisms in cortical axon growth, guidance and branching
Frontiers in Neuroanatomy, 2011 Precise wiring of cortical circuits during development depends upon axon extension, guidance and branching to appropriate targets. Motile growth cones at axon tips navigate through the nervous system by responding to molecular cues, which modulate ...
Katherine eKalil +5 more
doaj +1 more source
Motor axon guidance in Drosophila
Seminars in Cell & Developmental Biology, 2019 The Drosophila motor system starts to assemble during embryonic development. It is composed of 30 muscles per abdominal hemisegment and 36 motor neurons assembling into nerve branches to exit the CNS, navigate within the muscle field and finally establish specific connections with their target muscles. Several families of guidance molecules that play a
Aref, Arzan Zarin, Juan-Pablo, Labrador
openaire +4 more sources
Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting
Advanced Healthcare Materials, EarlyView.Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig +10 more
wiley +1 more source
Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGF(delta/delta) mouse model of amyotrophic lateral sclerosis [PDF]
, 2010 Background: Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that stimulates vasculogenesis. It has also been shown to act as a neurotrophic factor in vitro and in vivo.
Bender, F.L.P. +9 more
core +4 more sources
Expression of Genes Involved in Axon Guidance: How Much Have We Learned? [PDF]
, 2020 Sung Wook Kim, Kyong‐Tai Kim
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji +7 more
wiley +1 more source
Regulation of subcellular dendritic synapse specificity by axon guidance cues
eLife, 2019 Neural circuit assembly occurs with subcellular precision, yet the mechanisms underlying this precision remain largely unknown. Subcellular synaptic specificity could be achieved by molecularly distinct subcellular domains that locally regulate synapse ...
Emily C Sales +3 more
doaj +1 more source
Axon guidance: Crossing the midline [PDF]
Current Biology, 1998 Neurons that connect the two sides of the nervous system project their axons across the midline. New studies provide evidence for a conserved gatekeeping mechanism that controls this midline crossing.
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow +6 more
wiley +1 more source