Results 161 to 170 of about 899,641 (334)

Amino Acid‐Sensing Neurons in the Anterior Piriform Cortex Control Brown Adipose Tissue Thermogenesis

Advanced Science, EarlyView.
This study identifies a class of amino acid‐sensing neurons, APCCRH neurons, which regulate BAT thermogenesis. Leucine deficiency alters intrinsic excitability through GCN2 signaling pathway, activating APCCRH neurons, which in turn regulate BAT thermogenesis via projections to the lateral hypothalamus.
Peixiang Luo, Kexin Tong, Yeting Gan, Min Tang, Yuguo Niu, Kan Liu, Shihong Ni, Shangming Wu, Xiaoxue Jiang, Haizhou Jiang, Fei Xiao, Shanghai Chen, Wei Lv, Xiaoying Li, Feixiang Yuan, Feifan Guo   +15 more
wiley   +1 more source

Is microglial dystrophy a form of cellular senescence? An analysis of senescence markers in the aged human brain

Glia, Volume 71, Issue 2, Page 377-390, February 2023., 2023
Main Points Aging‐related morphological changes in microglia (dystrophy) do not correlate with expression of universal senescence markers. Microglial dystrophy coincides with an aging‐related increase in microglial ferritin expression. Abstract Aging can cause morphological transformation in human microglia indicative of cell senescence, termed ...
Pauline Neumann, Dana E. Lenz, Wolfgang J. Streit, Ingo Bechmann   +3 more
wiley   +1 more source

SnapShot: Axon Guidance

Cell, 2013
R. Jeroen Pasterkamp, Alex L. Kolodkin
openaire   +3 more sources

Computational and AI‐Driven Design of Hydrogels for Bioelectronic Applications

Advanced Electronic Materials, EarlyView.
This review highlights the role of AI in advancing hydrogel design for bioelectronics, exploring natural, and synthetic gels tailored for applications like wound healing, biosensing, and tissue engineering. It emphasizes the synergy between hydrogels, electronics, and AI in creating responsive, multifunctional systems, showcasing recent innovations ...
Rebekah Finster, Prashant Sankaran, Eloise Bihar   +2 more
wiley   +1 more source

Retinal regions shape human and murine Müller cell proteome profile and functionality

Glia, Volume 71, Issue 2, Page 391-414, February 2023., 2023
Main Points We defined Müller cells heterogeneity in the macular and peripheral human retina. Signaling pathways shaping this glial heterogeneity include proteins important for interaction with vesicular secretion, extracellular matrix and cell adhesion.
Lew Kaplan, Corinne Drexler, Anna M. Pfaller, Santra Brenna, Kirsten A. Wunderlich, Andrea Dimitracopoulos, Juliane Merl‐Pham, Maria‐Theresa Perez, Ursula Schlötzer‐Schrehardt, Volker Enzmann, Marijana Samardzija, Berta Puig, Peter Fuchs, Kristian Franze, Stefanie M. Hauck, Antje Grosche   +15 more
wiley   +1 more source

Interactions between genes involved in physiological dysregulation and axon guidance: role in Alzheimer's disease. [PDF]

Front Genet, 2023
Arbeev KG, Ukraintseva S, Bagley O, Duan H, Wu D, Akushevich I, Stallard E, Kulminski A, Christensen K, Feitosa MF, O'Connell JR, Parker D, Whitson H, Yashin AI.   +13 more
europepmc   +1 more source

Edge of Chaos Theory Unveils the First and Simplest Ever Reported Hodgkin–Huxley Neuristor

Advanced Electronic Materials, EarlyView.
This manuscript presents the first and simplest ever‐reported electrical cell, which leverages one memristor on Edge of Chaos to reproduce the three‐bifurcation cascade, marking the entire life cycle from birth to extinction via All‐to‐None effect of an electrical spike, also referred to as Action Potential, across axon membranes under monotonic ...
Alon Ascoli, Ahmet Samil Demirkol, Ioannis Messaris, Vasilis Ntinas, Dimitris Prousalis, Stefan Slesazeck, Thomas Mikolajick, Fernando Corinto, Michele Bonnin, Marco Gilli, Pier Paolo Civalleri, Ronald Tetzlaff, Leon Chua   +12 more
wiley   +1 more source

A subset of OPCs do not express Olig2 during development which can be increased in the adult by brain injuries and complex motor learning

Glia, Volume 71, Issue 2, Page 415-430, February 2023., 2023
Main Points A subset of OPCs do not express Olig2, of which population peaks in the juvenile brain while wanes with age. Plastic changes of the brain by acute injuries or complex motor learning stop the expression of Olig2 in OPCs. Abstract Oligodendrocyte precursor cells (OPCs) are uniformly distributed in the mammalian brain; however, their function ...
Li‐Pao Fang, Qing Liu, Erika Meyer, Anna Welle, Wenhui Huang, Anja Scheller, Frank Kirchhoff, Xianshu Bai   +7 more
wiley   +1 more source

Functions of netrins and semaphorins in axon guidance

, 1996
Joseph G. Culotti, Alex L. Kolodkin
openalex   +1 more source

Axon guidance at the midline of the developing CNS [PDF]

, 2000
Zaven Kaprielian, Ralph Imondi, Erik Runko   +2 more
openalex   +1 more source