Cytoskeletal Dynamics and Transport in Growth Cone Motility and Axon Guidance [PDF]
Erik W. Dent, Frank B. Gertler
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Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems
Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar+10 more
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FGF-Mediated Axon Guidance: Role of Downstream Signaling Pathways in Cytoskeletal Control. [PDF]
Li J, Gao H, Liu F.
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Efferocytosis is restricted by axon guidance molecule EphA4 via ERK/Stat6/MERTK signaling following brain injury. [PDF]
Soliman E+12 more
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Tenascin-R as a Repellent Guidance Molecule for Developing Optic Axons in Zebrafish [PDF]
Catherina G. Becker+4 more
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Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu+14 more
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Calcitriol Modulates Hippocampal Axon Guidance Through Enhanced EfnA4-Mediated PI3K/AKT Signaling in an Autism Mouse Model. [PDF]
Gong T+11 more
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Molecular insights into the axon guidance molecules Sidestep and Beaten path. [PDF]
Heymann C+5 more
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The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie+8 more
wiley +1 more source
Expanding ligand-receptor interaction networks for axon guidance: Structural insights into signal crosstalk and specificity. [PDF]
Zhu S, Jaworski A, Meijers R.
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