Results 181 to 190 of about 1,064,643 (248)

Homologous membrane wrapped ZIF‐8 nanoparticles accelerate differentiation of neural stem cell for spinal cord injury therapy

open access: yesBMEMat, EarlyView.
Homologous membrane wrapped ZIF‐8 nanoparticles were proposed to improve biocompatibility and targeting ability to neural stem cells (NSCs). ZIF‐8‐SCM NPs exhibit pH responsiveness, thereby generating an intracellular Zn2+ storm to accelerate neural differentiation through calcium and MAPK signaling pathways. Moreover, they promote function recovery in
Jie Wang   +11 more
wiley   +1 more source

Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system.

open access: yesCell, 1996
T. Serafini   +6 more
semanticscholar   +1 more source

Global Trends and Advances in Traumatic Brain Injury

open access: yesBrain Health, EarlyView.
ABSTRACT Traumatic brain injury (TBI) remains a major global public health challenge, contributing substantially to morbidity and mortality while imposing a significant socioeconomic burden. In recent years, notable progress has been made in understanding TBI pathophysiology, classification, monitoring, and treatment.
Yuan Zhuang   +3 more
wiley   +1 more source

Roundabout receptor signaling: beyond axon guidance

open access: yesSignal Transduction and Targeted Therapy
Naresh L. Selokar, Wilfried A. Kues
doaj   +1 more source

Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.

open access: yesCell, 1999
K. Brose   +7 more
semanticscholar   +1 more source

Vascularization of the Ulnar Nerve: Anatomical Feasibility as a Vascularized Nerve Graft for Contralateral C7 Transfer

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Recent advances in brachial plexus reconstruction have highlighted the potential advantages of vascularized nerve grafts for functional recovery in high‐priority nerve injuries. This anatomical study evaluated the extrinsic vascular supply of the ulnar nerve based on the superior ulnar collateral artery (SUCA) in the arm, aiming to assess its ...
M. Rosa Morro‐Martí   +7 more
wiley   +1 more source

Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor.

open access: yesHuman Molecular Genetics, 2015
H. Hor   +24 more
semanticscholar   +1 more source

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

open access: yesCytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham   +3 more
wiley   +1 more source

Visualizing Specific Tubulin Isotypes and Pathogenic Variants in Cellular Microtubule Arrays

open access: yesCytoskeleton, EarlyView.
ABSTRACT Eukaryotic cells depend on dynamic microtubule arrays to execute a wide range of functions vital for life. These microtubule filaments are formed through the polymerization of α/β‐tubulin proteins, which can be generated from numerous tubulin genes, or isotypes.
Sareen Fiaz   +2 more
wiley   +1 more source

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