Results 191 to 200 of about 50,714 (254)

Quercetin Alleviates Diabetic Peripheral Neuropathy by Regulating Axon Guidance Factors and Inhibiting the Rho/ROCK Pathway in vivo and in vitro. [PDF]

Diabetes Metab Syndr Obes
Song W, Li Y, Jia Y, Xu L, Kang L, Yang Y, Wang S, Zhang Q, Wu Q.   +8 more
europepmc   +1 more source

Vascularization of the Ulnar Nerve: Anatomical Feasibility as a Vascularized Nerve Graft for Contralateral C7 Transfer

Clinical Anatomy, EarlyView.
ABSTRACT Recent advances in brachial plexus reconstruction have highlighted the potential advantages of vascularized nerve grafts for functional recovery in high‐priority nerve injuries. This anatomical study evaluated the extrinsic vascular supply of the ulnar nerve based on the superior ulnar collateral artery (SUCA) in the arm, aiming to assess its ...
M. Rosa Morro‐Martí, Pablo Martínez‐Collado, Amer Mustafa‐Gondolbeu, Guillermo Tarnawski‐Español, Anna Carrera‐Burgaya, Joaquim Casañas‐Sintes, Anton Fornieles‐Espinel, Manuel Llusá‐Pérez   +7 more
wiley   +1 more source

Tet controls axon guidance in early brain development through glutamatergic signaling. [PDF]

iScience
Tran H, Le L, Singh BN, Kramer J, Steward R.   +4 more
europepmc   +1 more source

Donor‐To‐Recipient Mean Axonal Count Ratios of Upper Limb Nerves Used in Nerve Transfer Surgery: A Systematic Review of Histomorphometric Cadaveric Studies

Clinical Anatomy, EarlyView.
ABSTRACT Nerve transfer surgery may be performed to restore sensorimotor function following peripheral nerve trauma or dysfunction. There is biological plausibility and limited correlative evidence that donor‐to‐recipient axon count ratios may impact functional outcomes.
Samuel James Ng, Rosa Morgan‐Young, Alexander Laing, Rebecca Molden, Suzanne Thomson   +4 more
wiley   +1 more source

UNC5C: Novel Gene Associated with Psychiatric Disorders Impacts Dysregulation of Axon Guidance Pathways. [PDF]

Genes (Basel)
Treccarichi S, Failla P, Vinci M, Musumeci A, Gloria A, Vasta A, Calabrese G, Papa C, Federico C, Saccone S, Calì F.   +10 more
europepmc   +1 more source

Associations of Plasma Total Tau Level and MMSE Score With Polysomnographic Data in Middle‐Aged Men With Severe Obstructive Sleep Apnea: A Pilot Study

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background Obstructive sleep apnea (OSA) is one of the most common sleep disorders. Intermittent nocturnal hypoxia and sleep fragmentation in OSA may be among the main mechanisms triggering cognitive impairment and neurodegeneration. The study was to identify the relationships among plasma total tau (t‐tau) levels, Mini‐Mental State ...
Irina M. Madaeva, Alena A. Pytkina, Olga N. Berdina, Nadezhda A. Kurashova, Natalia V. Semenova, Luibov I. Kolesnikova   +5 more
wiley   +1 more source

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

Cytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham, Mihir Relan, Matthew T. Swulius, Andrea K. H. Stavoe   +3 more
wiley   +1 more source

A human DCC variant causing mirror movement disorder reveals that the WAVE regulatory complex mediates axon guidance by netrin-1-DCC. [PDF]

Sci Signal
Chaudhari K, Zhang K, Yam PT, Zang Y, Kramer DA, Gagnon S, Schlienger S, Calabretta S, Michaud JF, Collins M, Wang J, Srour M, Chen B, Charron F, Bashaw GJ.   +14 more
europepmc   +1 more source

Visualizing Specific Tubulin Isotypes and Pathogenic Variants in Cellular Microtubule Arrays

Cytoskeleton, EarlyView.
ABSTRACT Eukaryotic cells depend on dynamic microtubule arrays to execute a wide range of functions vital for life. These microtubule filaments are formed through the polymerization of α/β‐tubulin proteins, which can be generated from numerous tubulin genes, or isotypes.
Sareen Fiaz, Benjamin Powers, Jayne Aiken   +2 more
wiley   +1 more source

Longitudinal Clinical Progression in X‐Linked Adrenoleukodystrophy: The AMNL Scoring System

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective The current clinical nomenclature for individuals with ABCD1 gene dysfunction is often uninformative. The disorder was initially described as a combination of adrenal insufficiency and leukodystrophy, leading to the widespread use of “X‐linked adrenoleukodystrophy” (ALD).
Eda G. Kabak, Cecilie Videbaek, Marije M. C. Voermans, Björn M. van Geel, Keith van Haren, Stephan Kemp, Diederik van de Beek, Marc Engelen   +7 more
wiley   +1 more source