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Axonal guidance in the chicken retina
Development, 1995ABSTRACT During retina development, ganglion cells extend their axons exclusively into the innermost tissue layer, but not into outer retina layers. In order to elucidate guiding mechanisms for axons, tissue strips of embryonic chicken retinae were explanted onto retinal cryosections (cryoculture).
H, Stier, B, Schlosshauer
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Dynamic regulation of axon guidance
Nature Neuroscience, 2001To reach their proper targets, axons rely upon the actions of highly conserved families of attractive and repulsive guidance molecules, including the netrins, Slits, semaphorins and ephrins. These guidance systems are used to generate an astonishingly varied set of neuronal circuits.
T W, Yu, C I, Bargmann
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Axon guidance at choice points
Current Opinion in Neurobiology, 1998The common theme in many recent axonal pathfinding studies, both in vertebrates and invertebrates, is the demonstration of the importance of a balance between positive and negative cues. The integration of multiple and often opposing molecular interactions at each site along the axon's trajectory, especially at choice points, helps to fine tune the ...
Stoeckli, E T, Landmesser, L T
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Axon Guidance in the Dopamine System
2009Meso-diencephalic dopamine neurons (mdDA) neurons are located in the retrorubral field (RRF), substantia nigra pars compacta (SNc) and ventral tegmental area (VTA) and give rise to prominent ascending axon projections. These so-called mesotelencephalic projections are organized into three main pathways: the mesostriatal, mesocortical and mesolimbic ...
Asheeta A, Prasad, R Jeroen, Pasterkamp
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Axon guidance by molecular gradients
Current Opinion in Neurobiology, 1992In the past year, evidence indicating that some developing axons are guided to their targets, at least in part, by gradients of diffusible chemoattractants secreted by their target cells has continued to accumulate. It has also been shown for the first time that axons can orient in response to smooth gradients of immobilized substrate molecules.
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Expression of Genes Involved in Axon Guidance: How Much Have We Learned?
International Journal of Molecular Sciences, 2020Kyong-Tai Kim, Sung Wook Kim
exaly