Commissural axon guidance in the developing spinal cord: from Cajal to the present day
During neuronal development, the formation of neural circuits requires developing axons to traverse a diverse cellular and molecular environment to establish synaptic contacts with the appropriate postsynaptic partners.
J. D. Comer+3 more
doaj +1 more source
Future Frontiers in Bioinspired Implanted Biomaterials
Gu et al. present an integrative overview of cutting‐edge strategies in bioinspired implantable biomaterials for organ regeneration, highlighting how emerging approaches—including 3D bioprinting, scaffold design, hydrogel systems, surface modification, nanofiber engineering, and genetic manipulation—converge to restore structure and function across ...
Qi Gu+3 more
wiley +1 more source
TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation
Summary: Neuronal migration, axon fasciculation, and axon guidance need to be closely coordinated for neural circuit assembly. Spinal motor neurons (MNs) face unique challenges during development because their cell bodies reside within the central ...
Tracey A.C.S. Suter+5 more
doaj
3D Printing for Neural Repair: Bridging the Gap in Regenerative Medicine
This perspective article discusses how 3D bioprinting is advancing the development of neural tissue models and implants. It highlights recent progress in fabricating complex, multicellular neural constructs, examines current technical barriers, and outlines future applications in disease modeling, neurotoxicity testing, and regenerative therapies ...
Mitchell St Clair‐Glover+2 more
wiley +1 more source
Axon guidance in the inner ear
Statoacoustic ganglion (SAG) neurons send their peripheral processes to navigate into the inner ear sensory organs where they will ultimately become post-synaptic to mature hair cells. During early ear development, neuroblasts delaminate from a restricted region of the ventral otocyst and migrate to form the SAG.
Donna M. Fekete, Andrea M. Campero
openaire +4 more sources
Signaling mechanisms in cortical axon growth, guidance and branching
Precise wiring of cortical circuits during development depends upon axon extension, guidance and branching to appropriate targets. Motile growth cones at axon tips navigate through the nervous system by responding to molecular cues, which modulate ...
Katherine eKalil+5 more
doaj +1 more source
3D Printing of Conducting Polymer Hydrogels for Electrostimulation‐Assisted Tissue Engineering
This review highlights nanosized inherently conducting polymers (ICPs) as promising ink constituents for 3D printing of conducting hydrogel (CH)‐based electrostimulation (ES) devices. ICP‐based ink formulation, 3D printing, and solidification strategies are discussed, along with the application of 3D‐printed ICP‐based CHs as ES platforms for regulating
Chien Minh Tran+6 more
wiley +1 more source
Regulation of subcellular dendritic synapse specificity by axon guidance cues
Neural circuit assembly occurs with subcellular precision, yet the mechanisms underlying this precision remain largely unknown. Subcellular synaptic specificity could be achieved by molecularly distinct subcellular domains that locally regulate synapse ...
Emily C Sales+3 more
doaj +1 more source
Efficient and Realistic Brain Simulation: A Review and Design Guide for Memristor‐Based Approaches
Memristor‐based emulation of Hodgkin‐Huxley neuron models is investigated, by defining the ideal device characteristics needed for accurate ion‐channel representation and reviewing existing works targeting memristive replication of biological realistic neural behavior.
Lennart Paul Liong Landsmeer+5 more
wiley +1 more source
Guidance of callosal axons by radial glia in the developing cerebral cortex [PDF]
CR Norris, Katherine Kalil
openalex +1 more source