Results 81 to 90 of about 102,974 (302)
Highwire regulates guidance of sister axons in the drosophila mushroom body [PDF]
, 2011 Axons often form synaptic contacts with multiple targets by extending branches along different paths. PHR (Pam/Highwire/RPM-1) family ubiquitin ligases are important regulators of axon development, with roles in axon outgrowth, target selection, and ...
DiAntonio, Aaron, Shin, Jung Eun
core +2 more sources
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Neural Development, 2009 Background While many molecules involved in axon guidance have been identified, the cellular and molecular mechanisms by which these molecules regulate growth cone morphology during axon outgrowth remain to be elucidated.
Lundquist Erik A +2 more
doaj +1 more source
Defining the ligand specificity of the deleted in colorectal cancer (DCC) receptor. [PDF]
PLoS ONE, 2014 The growth and guidance of many axons in the developing nervous system require Netrin-mediated activation of Deleted in Colorectal Cancer (DCC) and other still unknown signaling cues.
Patrick C G Haddick +8 more
doaj +1 more source
Role of Netrin-1 Signaling in Nerve Regeneration. [PDF]
, 2017 Netrin-1 was the first axon guidance molecule to be discovered in vertebrates and has a strong chemotropic function for axonal guidance, cell migration, morphogenesis and angiogenesis.
Cajal +11 more
core +3 more sources
Microfluidic control of axonal guidance [PDF]
Scientific Reports, 2014 The precision of axonal pathfinding and the accurate formation of functional neural circuitry are crucial for an organism during development as well as during adult central and peripheral nerve regeneration. While chemical cues are believed to be primarily responsible for axonal pathfinding, we hypothesize that forces due to localized fluid flow may ...
Gu, Ling +5 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source
Plexin B3 guides axons to cross the midline in vivo
Frontiers in Cellular NeuroscienceDuring the development of neural circuits, axons are guided by a variety of molecular cues to navigate through the brain and establish precise connections with correct partners at the right time and place. Many axon guidance cues have been identified and
Zhi-Zhi Liu +21 more
doaj +1 more source
A simple rule for axon outgrowth and synaptic competition generates realistic connection lengths and filling fractions [PDF]
, 2009 Neural connectivity at the cellular and mesoscopic level appears very specific and is presumed to arise from highly specific developmental mechanisms.
Achacoso +64 more
core +2 more sources
Advanced Functional Materials, EarlyView.A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang +9 more
wiley +1 more source