Results 131 to 140 of about 28,691 (244)

Compartimentalized NF-kappaB activity in the axon initial segment

BMC Neuroscience, 2007
Prehn Jochen, Deller Thomas, Kögel Donat, Politi Chrisoula, Schwamborn Robert, König Hans-Georg, Schultz Christian   +6 more
doaj   +1 more source

Sodium channel endocytosis drives axon initial segment plasticity. [PDF]

Sci Adv, 2023
Fréal A, Jamann N, Ten Bos J, Jansen J, Petersen N, Ligthart T, Hoogenraad CC, Kole MHP.   +7 more
europepmc   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen   +11 more
wiley   +1 more source

Axon initial segment dynamics during associative fear learning. [PDF]

Nat Neurosci
Benoit CM, Ganea DA, Paricio-Montesinos R, Esser J, Thome C, Janssen JM, Sattin A, Innocenti SM, Krabbe S, Lüthi A, Fellin T, Engelhardt M, Gründemann J.   +12 more
europepmc   +1 more source

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, EarlyView.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

Reframing the axon initial segment: Giant ankyrin-G as a modulator of excitability and plasticity in neurodevelopment. [PDF]

Proc Natl Acad Sci U S A
Lopez AY, Jenkins PM.
europepmc   +1 more source

Maternal‐Fetal Administration of Risdiplam Partially Rescues the SMNΔ7 Mouse Model of Spinal Muscular Atrophy

Annals of Neurology, EarlyView.
Objective Spinal muscular atrophy (SMA) is caused by deletions or mutations in the survival motor neuron 1 (SMN1) gene and subsequent reduction in the expression of survival motor neuron (SMN) protein. The disease is characterized by degeneration of α motor neurons and subsequent muscle atrophy.
Emma R. Sutton, Ariane Beauvais, Rebecca Yaworski, Hugh J. McMillan, Rashmi Kothary   +4 more
wiley   +1 more source

Distribution of Voltage-Gated Sodium Channels and Scaffolding Proteins on Vestibular Calyx Ending Delineates the Axon Initial Segment. [PDF]

J Comp Neurol
Lysakowski A, Govindaraju AC, Price SD, Gaboyard-Niay S, Calin-Jageman I, Chidavaenzi RL, Eatock RA, Raphael RM, Goldberg JM.   +8 more
europepmc   +1 more source

Piezoelectric Nanocomposite Hydrogel for Wireless Neural Stimulation and Tissue Augmentation

Advanced NanoBiomed Research, EarlyView.
A cell/tissue supporting piezoelectric hydrogel system (PZ‐gel) that incorporates ferroelectric, pyroelectric, and piezoelectric ceramic material barium titanate into an alginate/carboxymethyl chitosan hydrogel. The PZ‐gel can be sonoactivated for wireless neural cell and tissue stimulation, with the potential to be used as a stimulatory cell substrate
Mohammad Mohammadi, Eva Tomaskovic‐Crook, Peter C. Innis, Jeremy M. Crook   +3 more
wiley   +1 more source

The axon initial segment-associated microglia regulate neuronal activity and visual perception. [PDF]

Cell Res
Wang Y, Wang Q, Gao C, He S, Wei C, Song J, Liu X, Liu X, Feng S, Yao W, Wu W, Gao TM, Ren S.   +12 more
europepmc   +1 more source