Results 201 to 210 of about 56,490 (282)

Polarity of varicosity initiation in central neuron mechanosensation [PDF]

, 2017
Akhmanova, Amack, Andrieux, Baas, Barry, Barry, Barsukova, Benfenati, Bentley, Betz, Beyder, Bosc, Bu, Campàs, Caterina, Chen Gu, Cho, Christensen, Chung, Cosens, Couégnas, David Brody, Debanne, DeFord, Delmas, Deloulme, Eastwood, Elkin, Engler, Fournet, Franze, Gao, Gardner, Gibson, Gilmour, Grevesse, Gu, Gu, Gu, Gu, Gu, Guillaud, Harrington, Hasbani, Hemphill, Iwata, Jukkola, Jukkola, Kanayama, Kang, Koleske, Laurer, Lefèvre, Liedtke, Liedtke, Ligon, Lu, Luo, Margolis, Montell, Morris, Namba, Nikić, Peter Jukkola, Pirollet, Qian Wang, Reeves, Richard, Rishal, Ryskamp, Serrano, Shepherd, Shibasaki, Shitaka, Smith, Staal, Strotmann, Sánchez, Tang-Schomer, Thomas Esparza, Tseng, van Beuningen, Van Essen, Venkatachalam, Wang, Wang, Xu, Xu, Yang, Yi Zhao, Yuanzheng Gu, Zheng, Ziv, Árnadóttir   +93 more
core   +2 more sources

Serum NfL, GFAP, and p‐tau217 in adults with drug‐resistant epilepsy and intellectual disabilities: Signs of ongoing neural injury

Epilepsia, EarlyView.
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie, Inge M. W. Verberk, Jans S. van Ool, Anneke J. J. Rampen, Rebecca Z. Rousset, Nicole I. Wolf, Dederieke A. M. Maes‐Festen, Clara D. M. van Karnebeek, Charlotte E. Teunissen, Erik Boot, Agnies M. van Eeghen   +10 more
wiley   +1 more source

Tsc1 deletion in Purkinje neurons disrupts the axon initial segment, impairing excitability and cerebellar function. [PDF]

Neurobiol Dis
Brown SP, Jena AK, Osko JJ, Ransdell JL.
europepmc   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

PVT1 lincRNA signals an androgen‐dependent transcriptional activation program of oncogenes in prostate cancer cells

International Journal of Cancer, EarlyView.
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho, Fabio Nunes de Mello, Ana Carolina Tahira, Gabriel Nakanishi Fortes, Agatha Fischer‐Carvalho, Pedro Jardim Poli, Murilo Sena Amaral, Sergio Verjovski‐Almeida   +7 more
wiley   +1 more source

A hierarchy of PDZ domain scaffolding proteins clusters the Kv1 K⁺ channel protein complex at the axon initial segment. [PDF]

Sci Adv
Zhang W, Palfini VL, Wu Y, Ding X, Melton AJ, Gao Y, Ogawa Y, Rasband MN.   +7 more
europepmc   +1 more source

Spatial multi‐omics identifies a NOTCH3‐mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma

iMeta, EarlyView.
Spatial multi‐omics defines a DLL4–NOTCH3–driven capillary–mCAF axis orchestrating fibrotic remodeling and immune exclusion in hepatocellular carcinoma tumor cores, conferring immune checkpoint blockade resistance. Targeting stromal NOTCH3 disrupts this pro‐fibrotic niche, enhances T cell infiltration, and synergizes with anti‐PD‐1 therapy ...
Fansen Ji, Haochen Li, Qi Wang, Xiaojuan Wang, Jiawei Zhang, Ying Xiao, Huan Li, Hao Liu, Tanqing Long, Boyang Wu, Hao Chen, Haoming Xia, Xinquan Liu, Chuanrui Xu, Yibo Gao, Bingjun Tang, Juan Liu, Shizhong Yang, Jiahong Dong   +18 more
wiley   +1 more source

Gradual volatile memristor–based artificial neurons with high uniformity for neuromorphic computing

InfoScience, EarlyView.
Schematic of leaky integrate‐and‐fire artificial neurons for MNIST image classification. Abstract Artificial neurons are pivotal for neuromorphic hardware, but the development of compact and uniform devices remains challenging. Conventional volatile memristors suffer from abrupt switching, which hinders spatiotemporal consistency.
Pengtao Li, Guobin Zhang, Zhihao Gong, Zijian Wang, Xuemeng Fan, Qi Luo, Zhejia Zhang, Dawei Gao, Mingkun Xu, Hua Wang, Shuai Zhong, Qing Wan, Yishu Zhang   +12 more
wiley   +1 more source

Motor learning changes the axon initial segment of the spinal motoneuron. [PDF]

J Physiol
Wang Y, Chen Y, Chen L, Herron BJ, Chen XY, Wolpaw JR.   +5 more
europepmc   +1 more source

Organic neuromorphic electronics powering intelligent sensory and edge computing systems

InfoMat, EarlyView.
Organic electronic materials are promising candidates for neuromorphic sensing applications, including chemical, physical, visual, and multimodal sensing, owing to their mechanical softness, biocompatibility, and intrinsic ionic–electronic coupling.
Seungjun Woo, Minji Chung, Hyun Woo Song, Seoyoung Kim, Eun Kwang Lee, Joon Hak Oh   +5 more
wiley   +1 more source