Results 191 to 200 of about 769,118 (313)
Genetically‐targeted control of the spinal cord and peripheral nervous system
Journal of Intelligent Medicine, EarlyView.Application of genetically‐targeted stimulation for treating diseases or injuries outside the brain. Optogenetic and chemogenetic systems have been developed for dysfunction in the cochlea, spinal cord, dorsal root ganglia (DRGs), peripheral nerves, lower urinary tract, and enteric nervous system (ENS). Created with Biorender.com.
Anakaren Romero Lozano +3 more
wiley +1 more source
MR‐Guidance of Gene Therapy for Brain Diseases: Moving From Palliative Treatment to Cures
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Regulatory bodies in the U.S. and Europe recently approved a gene therapy for aromatic L‐amino acid decarboxylase (AADC) deficiency, a rare neurologic disorder where a genetic mutation prevents dopamine production in the brain. Affected children fail to develop normal motor and cognitive functions.
Dalton H. Bermudez +2 more
wiley +1 more source
Tracing Axons in the Peripheral Nerve Using LacZ Gene Recombinant Adenovirus and Its Application to Regeneration of the Peripheral Nerve [PDF]
, 2001 Hitoshi Miwa +3 more
openalex +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Spinal cord injury (SCI) triggers secondary damage, including pain‐induced hypertension, inflammation, and hemorrhage, impairing recovery. This study evaluated the efficacy of general anesthesia with preemptive propofol administration in mitigating secondary damage in SCI rats. SCI was induced in rats using a contusion model.
Qun Cheng +2 more
wiley +1 more source
Repellent Guidance of Regenerating Optic Axons by Chondroitin Sulfate Glycosaminoglycans in Zebrafish [PDF]
, 2002 Catherina G. Becker, Thomas Becker
openalex +1 more source
Macromolecular Bioscience, EarlyView.Bioprinting offers a promising approach for repairing large peripheral nerve gap injuries, but suitable hydrogels remain limited. This study developed a visible light photocrosslinkable GelMA/PEGDA hybrid bioink and investigated how PEGDA molecular weight and concentration affect hydrogel properties.
Hexin Yue +4 more
wiley +1 more source
European Journal of Neurology, Volume 30, Issue 2, Page 511-526, February 2023., 2023 Abstract Background and purpose Charcot–Marie–Tooth disease (CMT) is a heterogeneous group of disorders caused by mutations in at least 100 genes. However, approximately 60% of cases with axonal neuropathies (CMT2) still remain without a genetic diagnosis. We aimed at identifying novel disease genes responsible for CMT2.
Silvia Cipriani +23 more
wiley +1 more source
Functional reconnections established by central respiratory neurons regenerating axons into a nerve graft bridging the respiratory centers to the cervical spinal cord [PDF]
, 2002 P. Gauthier +3 more
openalex +1 more source