Results 271 to 280 of about 38,776 (318)

Quantitative T1 is sensitive to cortical remyelination in multiple sclerosis: A postmortem MRI study

Brain Pathology, EarlyView.
In a post‐mortem study using multiparametric qMRI of whole fixed human brains from people with multiple sclerosis (pwMS), we found evidence that quantitative T1 (qT1) is sensitive to remyelination in the cortex. In contrast, QSM and radial diffusivity were affected by cortical pathology independently of remyelination. Our data suggest that qT1 could be
Riccardo Galbusera, Matthias Weigel, Erik Bahn, Sabine Schaedelin, Alessandro Cagol, Po‐Jui Lu, Muhamed Barakovic, Lester Melie‐Garcia, Jonas Franz, Peter Dechent, Govind Nair, Ludwig Kappos, Wolfgang Brück, Christine Stadelmann, Cristina Granziera   +14 more
wiley   +1 more source

Biphasic inflammation control by dedifferentiated fibroblasts enables axon regeneration after spinal cord injury in zebrafish

John N, Fleming T, Kolb J, Lyraki O, Vásquez-Sepúlveda S, Parmar A, Kim K, Tarczewska M, Gupta P, Singh K, Marini F, Singh SP, Falk S, Franze K, Guck J, Wehner D.   +15 more
europepmc   +1 more source

The role of microRNAs in axon regeneration after peripheral nerve injury: a bibliometric analysis. [PDF]

Front Neurol
Shoukeer K, Aierxiding S, Aisaiti A, Haibier A, Liu C, Jia Z, Aili A, Shu L, Jiang K, Muheremu A.   +9 more
europepmc   +1 more source

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison, Clauda Abboud, Dayana Abboud, Abdulrasheed O. Abdulrahman, Ana‐Nicoleta Bondar, Julie Dam, Zafiroula Georgoussi, Jesús Giraldo, Anemari Horvat, Christos Karoussiotis, Alba Paz‐Castro, Miriam Scarpa, Hannes Schihada, Nicole Scholz, Bilge Güvenc Tuna, Nina Vardjan   +15 more
wiley   +1 more source

Exercise-induced differential transcriptional output of AMPK signalling improves axon regeneration and functional recovery

Behera S, Ghosh Roy A.
europepmc   +1 more source

Appropriate patient population for future visual system axon regeneration therapies. [PDF]

WIREs Mech Dis
Bhattacharya SK, Alabiad CR, Kishor K.
europepmc   +1 more source

The epidermal growth factor receptor inhibitor gefitinib enhances in vitro and in vivo sensory axon regeneration and functional recovery following transection in a mouse median nerve injury model. [PDF]

Muscle Nerve
Topley M, Sparks P, Crotty AM, Kawaja M, Hendry JM.   +4 more
europepmc   +1 more source

The Dual Roles of Lamin A/C in Macrophage Mechanotransduction

Cell Proliferation, EarlyView.
Compressive force can inhibit the expression of lamin A/C, SUN1 and SUN2 in macrophages. Lamin A deficiency may participate in mechanotransduction within macrophages through two distinct mechanisms. ABSTRACT Cellular mechanotransduction is a complex physiological process that integrates alterations in the external environment with cellular behaviours ...
Yao Wang, Sabine Ruf, Lei Wang, Thomas Heimerl, Gert Bange, Sabine Groeger   +5 more
wiley   +1 more source

Neuroimmune modulating and energy supporting nanozyme-mimic scaffold synergistically promotes axon regeneration after spinal cord injury. [PDF]

J Nanobiotechnology
Zheng G, Yu W, Xu Z, Yang C, Wang Y, Yue Z, Xiao Q, Zhang W, Wu X, Zang F, Wang J, Wang L, Yuan WE, Hu B, Chen H.   +14 more
europepmc   +1 more source

Optineurin Cooperates With NRF2 to Regulate Tooth Root Morphogenesis by Controlling Mitochondrial Dynamics and Apoptosis

Cell Proliferation, EarlyView.
OPTN interacts with NRF2 to facilitate the AKT/DRP1‐mediated regulation of mitochondrial fission in the cytoplasm of SCAPs, promoting tooth root mineralisation. Additionally, OPTN maintains NRF2's nuclear translocation, enhancing the transcriptional regulation of downstream BCL2, ultimately leading to the inhibition apoptosis in SCAPs and regulate ...
Haojie Liu, Xinyu Zhang, Xiao Ge, ChingCho Hsu, Yan Wang, Simai Chen, Xingzhi Yan, Rongyao Xu, Junqing Ma, Shuyu Guo   +9 more
wiley   +1 more source