Results 101 to 110 of about 1,099,148 (284)

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez   +8 more
wiley   +1 more source

Diffusion Tensor Imaging Detects Acute and Subacute Changes in Corpus Callosum in Blast-Induced Traumatic Brain Injury

open access: yesASN Neuro, 2020
There is a critical need for understanding the progression of neuropathology in blast-induced traumatic brain injury using valid animal models to develop diagnostic approaches.
Palamadai N. Venkatasubramanian   +11 more
doaj   +1 more source

Comparative Clinical-Radiologic-Post mortem Study of Diffuse Axonal Injury in Severe Head Injury Patients [PDF]

open access: yes, 2015
BACKGROUND: To analyse the clinical, radiological and autopsy features of Diffuse Axonal Injury in severe head injury patients. MATERIAL AND METHODS: The patients who are admitted to the neurosurgical ward with Severe Head Injury (GCS < 8) and a CT ...
Palanisamy, S
core  

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez   +12 more
wiley   +1 more source

Traumatic Axonal Injury: Mechanisms and Translational Opportunities. [PDF]

open access: yes, 2016
Traumatic axonal injury (TAI) is an important pathoanatomical subgroup of traumatic brain injury (TBI) and a major driver of mortality and functional impairment. Experimental models have provided insights into the effects of mechanical deformation on the

core   +3 more sources

Biocompatible Conjugated Electrospinning Nanofibrous Membrane With Self‐Powered Piezoelectric Capacity for Accelerated Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
A self‐powered PCL/gelatin‐PVDF‐TrFE/MXene conjugated electrospun membrane integrates biocompatibility with enhanced piezoelectric responsiveness. Mechanical deformation is converted into localized electrical signals that stimulate wound‐repair cells proliferation and migration, promote angiogenesis and tissue remodeling, and accelerate full‐thickness ...
Diandian Li   +11 more
wiley   +1 more source

Diffuse axonal injury in brain trauma: insights from alterations in neurofilaments

open access: yesFrontiers in Cellular Neuroscience, 2014
Traumatic brain injury from penetrating or closed forces to the cranium can result in a range of forms of neural damage, which culminate in mortality or impart mild to significant neurological disability.
Declan Guenter Siedler   +9 more
doaj   +1 more source

Axonal Response to Traumatic Brain Injury: Reactive Axonal Change, Deafferentation, and Neuroplasticity

open access: yes, 1992
Axonal injury appears to be a feature common to all traumatic brain injuries, and has been linked to much of the morbidity seen in head-injured patients.
Daniel E. Erb   +2 more
core   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

open access: yesAdvanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong   +12 more
wiley   +1 more source

Role of calpains in the injury-induced dysfunction and degeneration of the mammalian axon

open access: yesNeurobiology of Disease, 2013
Axonal injury and degeneration, whether primary or secondary, contribute to the morbidity and mortality seen in many acquired and inherited central nervous system (CNS) and peripheral nervous system (PNS) disorders, such as traumatic brain injury, spinal
Marek Ma
doaj   +1 more source

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