Results 91 to 100 of about 1,099,148 (284)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

Added Value of Tissue Level Brain Injury Criteria

open access: yesInternational Journal of Automotive Engineering, 2019
Traumatic brain injury (TBI) is the leading cause of death and permanent impairment over the last decades. In both the severe and mild TBI, diffuse axonal injury (DAI) is the most common pathology.
Caroline Deck, Rémy Willinger
doaj   +1 more source

Diffuse Axonal Injury After Traumatic Brain Injury

open access: yes, 2004
Forty children and adolescents with traumatic brain injury and suspected diffuse axonal injury were studied for hemorrhagic lesions, using a high-resolution magnetic resonance imaging susceptibility-weighted technique, at Loma Linda University Medical ...
J Gordon Millichap
core   +1 more source

Fiber‐Based Wearable Electronics as Adaptive Biointerfaces for Healthcare Applications

open access: yesAdvanced Functional Materials, EarlyView.
Fiber‐based wearable electronics have been extensively studied as adaptive healthcare biointerfaces. In this review, we classify and introduce fiber‐based systems according to biointerface design, conductive materials, transduction mechanisms, and healthcare applications, and provide a perspective on their translation toward reliable, continuous ...
Sangwoo Hong   +5 more
wiley   +1 more source

Damage to Myelin and Oligodendrocytes: A Role in Chronic Outcomes Following Traumatic Brain Injury?

open access: yesBrain Sciences, 2013
There is increasing evidence in the experimental and clinical traumatic brain injury (TBI) literature that loss of central myelinated nerve fibers continues over the chronic post-traumatic phase after injury.
William L. Maxwell
doaj   +1 more source

A Delayed Presentation of Diffuse Axonal Injury

open access: yes, 2021
Diffuse axonal injury is one of the most common and debilitating pathologies resulting from mechanical deformation of the brain.  The current case involves a 19-year-old female involved in a high velocity ski crash.
Wunder, Meaghan, Ruicci, Kara
core  

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

Possible Coexistence of Traumatic Cerebral Microbleeds and Axonal Injury? Postmortem Immunohistochemical Analysis

open access: yesArab Journal of Forensic Sciences & Forensic Medicine
Diffuse axonal injury (DAI) is a common type of traumatic brain injury, whose detection remains a significant clinical challenge. Recent studies suggest that traumatic cerebral microbleeds (TCMs) may serve as indirect indicators of axonal injury.
Dalibor Nedić   +2 more
doaj   +1 more source

Neurogenesis and apoptosis in the developmentally regulated loss of spinal cord regeneration. [PDF]

open access: yes, 2006
Unlike the adult mammal, the chick can successfully regenerate its spinal cord until embryonic day (E) 13. Multiple factors may contribute to the subsequent loss of regenerative capacity, although most research has concentrated on axonal re-growth ...
Whalley, K.A., Whalley, Katherine Ann
core  

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu   +4 more
wiley   +1 more source

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