Results 181 to 190 of about 1,099,148 (284)

Study of Axonal Injury and Degeneration in <i>Drosophila</i>. [PDF]

Cold Spring Harb Protoc
Waller TJ, Smithson LJ, Collins CA.
europepmc   +1 more source

Membrane‐Targeted Nanoparticles for Neuronal Photomodulation

Advanced Science, EarlyView.
Immobilizing gold nanoparticles on the neural interface using a bioorthogonal approach generates localized heat upon exposure to near‐infrared light, temporarily inhibiting primary neuronal activity without damaging the cells. This precise placement and retention of nanoparticles at the cell membrane expand the strategies for non‐invasive neural ...
Ane Escobar, Ana Sánchez‐Iglesias, Davide Bello, Miriam Feijoo Barriga, Alex M. Ascensión, Laura Rodríguez‐Gómez, David Otaegui‐Bichot, Francisco Javier Gil‐Bea, Monica Carril, Marek Grzelczak   +9 more
wiley   +1 more source

Correction: Inhibitor of Apoptosis-Stimulating Protein of p53 (iASPP) Is Required for Neuronal Survival after Axonal Injury. [PDF]

PLoS One
Wilson AM, Chiodo VA, Boye SL, Brecha NC, Hauswirth WW, Di Polo A.   +5 more
europepmc   +1 more source

Blood‐Based Biomarkers in Alzheimer's Disease: Advances in Detection Technologies and Clinical Applications

AGING MEDICINE, EarlyView.
Blood‐based biomarkers are emerging as accessible tools for Alzheimer's disease screening, diagnosis, risk stratification, and longitudinal monitoring. This review summarizes major biomarkers, including Aβ42/Aβ40, phosphorylated tau species, NfL, GFAP, genetic risk markers, and exploratory inflammatory, synaptic, and proteomic candidates.
Shuangshuang Li, Lin Huang, Qihao Guo
wiley   +1 more source

Blast Overpressure-Induced Neuroinflammation and Axonal Injury in the Spinal Cord of Ferrets. [PDF]

Brain Sci
Phuyal G, Pundkar CY, Govindarajulu MY, Thanapaul RJRS, Al-Lami A, Menon A, Long JB, Arun P.   +7 more
europepmc   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen   +11 more
wiley   +1 more source

Myelin injury precedes axonal injury and symptomatic onset in multiple sclerosis. [PDF]

Nat Med
Abdelhak A, Cerono G, Sheikhzadeh F, Harroud A, Ning K, Zamecnik CR, Sowa GM, Boscardin J, Cordano C, Tubati A, Fouassier C, Chow ED, Gomez R, Santaniello A, Zorn KC, Hollenbach JA, Oksenberg JR, Cree BAC, Hauser SL, Chan JR, Baranzini SE, Wallin MT, Wilson MR, Green AJ.   +23 more
europepmc   +1 more source

Animal models for investigating post‐stroke cognitive impairment: A neurovascular trafficking perspective

Animal Models and Experimental Medicine, EarlyView.
Animal models enable mechanistic testing of how ischemic injury disrupts neurovascular trafficking and drives cognitive vulnerability after stroke. Complementary models capture distinct vascular, cellular, white matter, and cognitive features of PSCI.
Pratchaya Kaewkaen
wiley   +1 more source

Markers of axonal injury in blood and tissue triggered by acute and chronic demyelination. [PDF]

Brain
Abdelhak A, Cordano C, Duncan GJ, Emberley K, Nocera S, Xin W, Ananth K, Jabassini N, Ning K, Reinsberg H, Oertel FC, Beaudry-Richard A, Kuhle J, Petzold A, Patel PJ, Ribeiro Reis AP, Foster PJ, Watkins T, Chan JR, Emery B, Green AJ.   +20 more
europepmc   +1 more source

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source