Results 201 to 210 of about 122,498 (328)

Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons. [PDF]

Mol Neurobiol, 2023
Christensen KR, Combs B, Richards C, Grabinski T, Alhadidy MM, Kanaan NM.   +5 more
europepmc   +1 more source

Release of Kinesin from Vesicles by hsc70 and Regulation of Fast Axonal Transport [PDF]

, 2000
Ming-Ying Tsai, Gerardo Morfini, Györgyi Szebenyi, Scott T. Brady   +3 more
openalex   +1 more source

A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain

Advanced Science, EarlyView.
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria, Cristina Iglesias, Sascha Jung, Javier Arcos Hodar, Ruben Nogueiras, Antonio del Sol   +5 more
wiley   +1 more source

Single nucleotide polymorphisms in the CDH18 gene affect growth traits in Hu sheep

Animal Research and One Health, EarlyView., 2023
Abstract Growth traits are critical economic traits in sheep. Genetic polymorphism has a great influence on the improvement of sheep traits. The aim of this study was to analyze the effect of cadherin 18 (CDH18) gene polymorphisms on growth traits in Hu sheep.
Tianyi Liu, Yazhen Bi, Jingjing Bao, Mingyu Shang, Wenping Hu, Li Zhang   +5 more
wiley   +1 more source

Direct observation of importin α family member KPNA1 in axonal transport with or without a schizophrenia-related mutation. [PDF]

J Biol Chem
Mizuno K, Sugahara M, Kutomi O, Kato R, Itoh T, Fujita S, Yamada M.   +6 more
europepmc   +1 more source

Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes. [PDF]

Cell Rep, 2023
Dou D, Smith EM, Evans CS, Boecker CA, Holzbaur ELF.   +4 more
europepmc   +1 more source

Kinesin-Dependent Axonal Transport Is Mediated by the Sunday Driver (SYD) Protein [PDF]

, 2000
Aaron B. Bowman, Adeela Kamal, Bruce W. Ritchings, Alastair Valentine Philp, Maura McGrail, Joseph G. Gindhart, Lawrence S.B. Goldstein   +6 more
openalex   +1 more source

3D‐Printing of Electroconductive MXene‐Based Micro‐Meshes in a Biomimetic Hyaluronic Acid‐Based Scaffold Directs and Enhances Electrical Stimulation for Neural Repair Applications

Advanced Science, EarlyView.
This study combined microscale 3D‐printing with 2D Ti3C2Tx MXene nanosheets to produce electroconductive microfibrous micro‐meshes. By embedding these MXene‐functionalized micro‐meshes within a growth‐supportive macroporous extracellular matrix (ECM)‐based biomaterial, multifunctional biomimetic MXene‐ECM scaffolds were developed.
Ian Woods, Dahnan Spurling, Sandra Sunil, Anne Marie O'Callaghan, Jack Maughan, Javier Gutierrez‐Gonzalez, Tara K. McGuire, Liam Leahy, Adrian Dervan, Valeria Nicolosi, Fergal J. O'Brien   +10 more
wiley   +1 more source

Multi‐omics analyses reveal the interaction between colonic microbiota and host in Min and Yorkshire pigs

Animal Research and One Health, EarlyView., 2023
In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang, Huihui Li, Feng Cheng, Ligang Wang, Guoqing Cao, Lixian Wang, Lijun Shi   +6 more
wiley   +1 more source

Impaired axonal transport contributes to neurodegeneration in a Cre-inducible mouse model of myocilin-associated glaucoma. [PDF]

JCI Insight
Kaipa BR, Kasetti R, Sundaresan Y, Li L, Yacoub S, Millar JC, Cho W, Skowronska-Krawczyk D, Maddineni P, Palczewski K, Zode GS.   +10 more
europepmc   +1 more source