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Axonal Transport

2021
Abstract Axonal transport is fundamental for neuronal survival and maintenance of neuronal connectivity and synaptic function. Anterograde transport delivers membrane-bound organelles synthesized and packaged in the cell body to the axon and synaptic compartments, and also allows traffic and turnover of cytoskeletal and metabolic ...
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A paradigm for axonal transport

Neurochemical Research, 1983
Axonal transport has been extensively studied for a period of 20-30 years, but there is still no general consensus concerning the mechanism by which this transport process operates. An important development in this regard is the recent studies in the physical biochemistry group in the Department of Biochemistry at Monash University where it has been ...
W D, Comper, B N, Preston, L, Austin
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Retrograde Axonal Transport

1983
Intracellular movement of organelles is one of the fundamental characteristics of living cells. It is indispensable for the efficient distribution of materials and thus for the proper cellular function of eucaryotic cells, which are highly organized entities in which many functions are compartmentalized and carried out by specific substructures.
Martin E. Schwab, Hans Thoenen
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Axonal transport in neurological disease

Annals of Neurology, 1988
AbstractThe axonal transport systems have a wide variety of primary roles and secondary responses in neurological disease processes. Recent advances in understanding these roles have built on the increasingly detailed insights into the cell biology of the axon and its supporting cells.
J W, Griffin, D F, Watson
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Axonal transport and the cytoskeleton

Current Opinion in Neurobiology, 1993
Great advances in the field of axonal transport have been made in the past year, including the identification of new molecular motors associated with microtubules and actin. In addition, studies on the mechanisms of bidirectional fast axonal transport have clarified new aspects of this process, such as the isolation of a kinesin-binding protein ...
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Axonal transport

Current Opinion in Cell Biology, 1989
S, Okabe, N, Hirokawa
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Retrograde axonal transport of mercury

Experimental Neurology, 1987
Female Wistar rats were injected in the tongue with a small volume of 203Hg and were killed 2 weeks later. The lower brain stem with the hypoglossal nuclei was removed and sectioned in a cryostat. Autoradiography of freeze-dried sections showed labeling of both hypoglossal nuclei.
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Retrograde Axonal Transport

1980
Publisher Summary This chapter focuses on retrograde axonal transport. The study of retrograde axonal transport (RT) forms a significant part of research efforts in the neurosciences. There are two fundamentally important points of neuron: (1) the neuron is a very elongated cell and (2) the neuron is internally specialized according to function.
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Axonal transport

General Pharmacology: The Vascular System, 1976
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